14-3-3 proteins exert an extraordinarily widespread influence on cellular processes in all
eukaryotes. They operate by binding to specific phosphorylated sites on diverse target …

The genetic basis is now known for several disorders of neuronal migration in the
developing cerebral cortex. Identification of the cellular processes mediated by the …

The proprotein convertase PCSK9 gene is the third locus implicated in familial
hypercholesterolemia, emphasizing its role in cardiovascular diseases. Loss of function …

Abstract Disrupted in Schizophrenia 1 (DISC1) is a schizophrenia risk gene associated with
cognitive deficits in both schizophrenics and the normal ageing population. In this study, we …

In a large Scottish pedigree, a balanced translocation t (1; 11)(q42. 1; q14. 3) segregates
with major mental illness, including schizophrenia, bipolar disorder, and recurrent major …

The recent application of neuroimaging techniques in the field of human cognitive
development is providing the practical basis for researchers to face speculative queries that …

Psychotic disorders affect~ 3% of the general population and are among the most severe
forms of mental diseases. In early stages of psychosis, clinical aspects may be difficult to …

Dysfunction of the LIS1 gene causes lissencephaly, a drastic neurological disorder
characterized by a deep disruption of the cortical structure. We aim to uncover alterations of …

Nuclear distribution element‐like 1 (Ndel1 or Nudel) was firstly described as a regulator of
the cytoskeleton in microtubule and intermediate filament dynamics and microtubule‐based …

LIS1 is one of the principal genes related to Type I lissencephaly, a severe human brain
malformation characterized by an abnormal neuronal migration in the cortex during …