Terbinafine, an orally and topically active antimycotic agent, inhibits the biosynthesis of the
principal sterol in fungi, ergosterol, at the level of squalene epoxidase. Squalene epoxidase …

Onychomycosis is a fungal nail infection caused by dermatophytes, nondermatophyte
molds, and yeasts. This difficult‐to‐treat chronic infection has a tendency to relapse despite …

Terbinafine is an allylamine antifungal agent which has fungicidal activity against a wide
variety of dermatophytes, moulds and certain dimorphic fungi, and fungistatic activity against …

Objective To analyze studies on oral treatment of toenail onychomycosis so as to aid
clinicians and patients in making informed decisions. Data Sources Studies dealing with …

Clinicians now have five oral antifungal therapeutic agents to choose from when assessing
the risk–benefits associated with a particular treatment for onychomycosis (OM): griseofulvin …

Background: Onychomycosis is one of the early manifestations of HIV infection with a
prevalence of 15-40%. Multiple nail involvement, isolation of both common and rare species …

Onychomycosis is a fungal nail infection caused by dermatophytes, non-dermatophyte
molds, and yeasts. Treatment of this infection can be difficult, with relapse likely to occur …

Background It is not known whether human immunodeficiency virus (HIV) infection is
associated with an increased susceptibility to dermatophytes. Methods In this study, we …

Introduction Terbinafine has been a cornerstone in dermatophyte infection treatment.
Despite its global efficacy, the emergence of terbinafine resistance raises concerns …

Background The prevalence of onychomycosis is higher in certain high‐risk populations,
such as the immunocompromised, diabetics and human immunodeficiency virus (HIV) …