Simple indole alkaloids and those with a nonrearranged monoterpenoid unit

T Kawasaki, K Higuchi - Natural product reports, 2005 - pubs.rsc.org
Simple indole alkaloids and those with a nonrearranged monoterpenoid unit - Natural Product
Reports (RSC Publishing) DOI:10.1039/B502162F Royal Society of Chemistry View PDF …

Fischer indole synthesis applied to the total synthesis of natural products

MM Heravi, S Rohani, V Zadsirjan, N Zahedi - RSC advances, 2017 - pubs.rsc.org
One of the oldest and most useful reactions in organic chemistry is the Fischer indole
synthesis (FIS). It is known to have a wide variety of applications including the synthesis of …

[HTML][HTML] Synthesis of indole derivatives as prevalent moieties present in selected alkaloids

MM Heravi, Z Amiri, K Kafshdarzadeh, V Zadsirjan - RSC advances, 2021 - pubs.rsc.org
Indoles are a significant heterocyclic system in natural products and drugs. They are
important types of molecules and natural products and play a main role in cell biology. The …

Enantioselective palladium-catalyzed allylic alkylation reactions in the synthesis of Aspidosperma and structurally related monoterpene indole alkaloids

BP Pritchett, BM Stoltz - Natural product reports, 2018 - pubs.rsc.org
Covering: up to the end of 2017 Enantioselective Pd-catalyzed allylic alkylations of prochiral
enolates represent a powerful tool for the construction of all-carbon quaternary …

Total syntheses of (−)-mersicarpine,(−)-scholarisine G,(+)-melodinine E,(−)-leuconoxine,(−)-leuconolam,(−)-leuconodine A,(+)-leuconodine F, and (−)-leuconodine C …

Z Xu, Q Wang, J Zhu - Journal of the American Chemical Society, 2015 - ACS Publications
Enantioselective total syntheses of title natural products from a common cyclohexenone
derivative (S)-18 were reported. Ozonolysis of (S)-18 afforded a stable diketo ester (R)-17 …

[HTML][HTML] Applications of Friedel–Crafts reactions in total synthesis of natural products

MM Heravi, V Zadsirjan, P Saedi, T Momeni - RSC advances, 2018 - pubs.rsc.org
Over the years, Friedel–Crafts (FC) reactions have been acknowledged as the most useful
and powerful synthetic tools for the construction of a special kind of carbon–carbon bond …

Palladium-Catalyzed sp3 CH Activation of Simple Alkyl Groups: Direct Preparation of Indoline Derivatives from N-Alkyl-2-bromoanilines

T Watanabe, S Oishi, N Fujii, H Ohno - Organic Letters, 2008 - ACS Publications
The sp3 C− H activation of a simple alkyl group catalyzed by palladium (0) provides a novel
and convenient strategy for the synthesis of various indolines from simple precursors, such …

Biologically Active Indole Alkaloids from Kopsia arborea

KH Lim, O Hiraku, K Komiyama, T Koyano… - Journal of natural …, 2007 - ACS Publications
Nine new indole alkaloids, rhazinoline (1), 19 (S)-methoxytubotaiwine (2), 19 (R)-
methoxytubotaiwine (3), kopsamidine A (4), kopsamidine B (5), kopsinidine A (6) …

Total synthesis of (−)-mersicarpine

R Nakajima, T Ogino, S Yokoshima… - Journal of the American …, 2010 - ACS Publications
The total synthesis of (−)-mersicarpine was achieved in 10 steps from a known ketoester.
Our synthesis features an Eschenmoser− Tanabe-type fragmentation to synthesize an …

Biosynthetically inspired divergent approach to monoterpene indole alkaloids: total synthesis of mersicarpine, leuconodines B and D, leuconoxine, melodinine E …

Y Yang, Y Bai, S Sun, M Dai - Organic letters, 2014 - ACS Publications
Inspired by their potential biosynthesis, we have developed divergent total syntheses of
seven monoterpene indole alkaloids including mersicarpine, leuconodines B and D …