Design of Stimuli‐Responsive Peptides and Proteins

Y Li, G Yang, L Gerstweiler, SH Thang… - Advanced Functional …, 2023 - Wiley Online Library
Stimuli‐responsive peptides and proteins are an exciting class of smart biomaterials for
various applications and have received significant attention over the past decades. A wide …

Protein engineering in the development of functional hydrogels

S Banta, IR Wheeldon, M Blenner - Annual review of biomedical …, 2010 - annualreviews.org
Proteins, which are natural heteropolymers, have evolved to exhibit a staggering array of
functions and capabilities. As scientists and engineers strive to tackle important challenges …

[图书][B] The structure of biological membranes

PL Yeagle - 2004 - taylorfrancis.com
Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

Genetic Modification of Acidithiobacillus ferrooxidans for Rare-Earth Element Recovery under Acidic Conditions

H Jung, Z Su, Y Inaba, AC West… - Environmental Science & …, 2023 - ACS Publications
As global demands for rare-earth elements (REEs) continue to grow, the biological recovery
of REEs has been explored as a promising strategy, driven by potential economic and …

Structure–Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes

J Novak, O Cerny, A Osickova, I Linhartova, J Masin… - Toxins, 2017 - mdpi.com
Bordetellae, pathogenic to mammals, produce an immunomodulatory adenylate cyclase
toxin–hemolysin (CyaA, ACT or AC-Hly) that enables them to overcome the innate immune …

Calcium, acylation, and molecular confinement favor folding of Bordetella pertussis adenylate cyclase CyaA toxin into a monomeric and cytotoxic form

JC Karst, VYN Enguéné, SE Cannella, O Subrini… - Journal of Biological …, 2014 - ASBMB
The adenylate cyclase (CyaA) toxin, a multidomain protein of 1706 amino acids, is one of
the major virulence factors produced by Bordetella pertussis, the causative agent of …

Calcium-induced folding and stabilization of the intrinsically disordered RTX domain of the CyaA toxin

A Chenal, JC Karst, ACS Pérez, AK Wozniak, B Baron… - Biophysical …, 2010 - cell.com
The adenylate cyclase toxin (CyaA) is one of the major virulence factors of Bordetella
pertussis, the causative agent of whooping cough. Its C-terminal region, the receptor-binding …

Characterization of a membrane-active peptide from the Bordetella pertussis CyaA toxin

O Subrini, AC Sotomayor-Pérez, A Hessel… - Journal of Biological …, 2013 - ASBMB
Bordetella pertussis, the pathogenic bacteria responsible for whooping cough, secretes
several virulence factors, among which is the adenylate cyclase toxin (CyaA) that plays a …

Stability, structural and functional properties of a monomeric, calcium–loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis

SE Cannella, VY Ntsogo Enguéné, M Davi… - Scientific reports, 2017 - nature.com
Bordetella pertussis, the causative agent of whooping cough, secretes an adenylate cyclase
toxin, CyaA, which invades eukaryotic cells and alters their physiology by cAMP …

Structure–function relationships of the repeat domains of RTX toxins

U Baumann - Toxins, 2019 - mdpi.com
RTX proteins are a large family of polypeptides of mainly Gram-negative origin that are
secreted into the extracellular medium by a type I secretion system featuring a non …