Simple Summary Cancer is one of the hardest pathologies to fight, being one of the main
causes of death worldwide despite the constant development of novel therapeutic strategies …

In the process of cancer EMT, some subgroups of cancer cells simultaneously exhibit both
mesenchymal and epithelial characteristics, a phenomenon termed partial EMT (pEMT) …

Bladder cancer (BlCa) is a highly immunogenic cancer. Bacillus Calmette-Guérin (BCG) is
the standard treatment for non-muscle invasive bladder cancer (NMIBC) patients and …

Aberrant splicing events are associated with colorectal cancer (CRC) and provide new
opportunities for tumor diagnosis and treatment. The expression of the splice variants of NF …

Cadherins mediate cell–cell adhesion through a dynamic process that is strongly dependent
on the cellular context and signaling. Cadherin regulation reflects the interplay between …

Epithelial-mesenchymal plasticity (EMP) refers to the ability of cells to dynamically
interconvert between epithelial (E) and mesenchymal (M) phenotypes, thus generating an …

Spatial transcriptomics is revolutionizing the exploration of intratissue heterogeneity in
cancer, yet capturing cellular niches and their spatial relationships remains challenging. We …

Traditionally, lymphovascular invasion (LVI) has represented one of the foremost
pathological features of malignancy and has been associated with a worse prognosis in …

Immune evasion—a well-established cancer hallmark—is a major barrier to immunotherapy
efficacy. While the molecular mechanisms and biological consequences underpinning …

The epithelial–mesenchymal transition (EMT) is closely associated with the acquisition of
aggressive traits by carcinoma cells and is considered responsible for metastasis, relapse …