Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Exploring the structure and dynamics of biomolecules in the context of their intracellular
environment has become the ultimate challenge for structural biology. As the cellular …

Protein structure investigations are usually carried out in vitro under conditions far from their
native environment in the cell. Differences between in-cell and in vitro structures of proteins …

The cellular environment of proteins differs considerably from in vitro conditions under which
most studies of protein structures are carried out. Therefore, there is a growing interest in …

From the early days of CEST agents' disclosure, it was evident that their potential for in vivo
applications was strongly hampered by the intrinsic low sensitivity. Therefore, much work …

Background Large‐and small‐headed sperm are common morphological abnormalities. If
different sperm staining methods affect sperm size, they will make a difference in the …

Peptide materials based on the aggregation of polyphenylalanine conjugates containing
gadolinium complexes and acting as potential contrast agents (CAs) in magnetic resonance …

A new bismuth-based CT agent was synthesized through a facile synthesis strategy. The in
vitro stability, toxicity and CT performance were evaluated. The in vivo imaging performance …

Intracellular delivery of membrane‐impermeable cargo offers unique opportunities for
biological research and the development of cell‐based therapies. Despite the breadth of …

Magnetic resonance imaging (MRI) is a preferred technique for noninvasively monitoring the
fate of implanted cells, such as stem cells and immune cells in vivo. Cellular MRI requires …