NETosis in parasitic infections: A puzzle that remains unsolved

M Omar, H Abdelal - International Journal of Molecular Sciences, 2023 - mdpi.com
Neutrophils are the key players in the innate immune system, being weaponized with
numerous strategies to eliminate pathogens. The production of extracellular traps is one of …

Metabolomics and lipidomics studies of parasitic helminths: molecular diversity and identification levels achieved by using different characterisation tools

P Wangchuk, K Yeshi, A Loukas - Metabolomics, 2023 - Springer
Introduction Helminths are parasitic worms that infect millions of people worldwide and
secrete a variety of excretory-secretory products (ESPs), including proteins, peptides, and …

Advancing vaccine development against Opisthorchis viverrini: A synergistic integration of omics technologies and advanced computational tools

A Kafle, SC Ojha - Frontiers in Pharmacology, 2024 - frontiersin.org
The liver fluke O. viverrini (Opisthorchis viverrini), a neglected tropical disease (NTD),
endemic to the Great Mekong Subregion (GMS), mainly afflicts the northeastern region of …

Helminth-derived biomolecules as potential therapeutics against ulcerative colitis

A Chakraborty, J Bayry, S Mukherjee - Immunotherapy, 2024 - Taylor & Francis
'Helminth therapy'has been in the limelight over the last two decades. Extensive research
has unveiled the tendency of helminth and helminth derivatives to interact with various arms …

Gastrointestinal worms and bacteria: From association to intervention

J Rooney, C Cantacessi, J Sotillo… - Parasite …, 2023 - Wiley Online Library
A plethora of studies, both experimental and epidemiological, have indicated the occurrence
of associations between infections by gastrointestinal (GI) helminths and the composition …

Immunoblotting Identification of Diagnostic Antigens of Paragonimus westermani Type 1 for the Detection of Human Pulmonary Paragonimiasis in North East India

KR Devi, A Deka, D Mukherjee, H Kaur… - Tropical Medicine and …, 2023 - mdpi.com
Human pulmonary paragonimiasis, an emerging concern in North East India, frequently
masquerades as pulmonary tuberculosis due to clinical and radiological similarities, leading …

[HTML][HTML] Techniques, Databases and Software Used for Studying Polar Metabolites and Lipids of Gastrointestinal Parasites

P Wangchuk, K Yeshi - Animals, 2024 - mdpi.com
Simple Summary Gastrointestinal parasites (GIPs) coevolved with mammalian hosts over
millennia. These parasites produce small molecules, peptides, and proteins not only to …

Metabolite profiling of Trichinella spiralis adult worms and muscle larvae identifies their excretory and secretory products

N Uthailak, P Adisakwattana, P Chienwichai… - Frontiers in Cellular …, 2023 - frontiersin.org
Human trichinellosis is a parasitic infection caused by roundworms belonging to the genus
Trichinella, especially Trichinella spiralis. Early and accurate clinical diagnoses of …

[HTML][HTML] Unveiling Novel Insights in Helminth Proteomics: Advancements, Applications, and Implications for Parasitology and Beyond

N Soleymani, S Sadr, C Santucciu, S Dianaty… - Biologics, 2024 - mdpi.com
Helminths have developed intricate mechanisms to survive and evade the host's immune
responses. Hence, understanding the excretory-secretory products (ESPs) by helminths is …

Chronic small intestinal helminth infection perturbs bile acid homeostasis and disrupts bile acid signaling in the murine small intestine

JM Lane, TP Brosschot, DM Gatti, CM Gauthier… - Frontiers in …, 2023 - frontiersin.org
Intestinal helminths have evolved an abundance of immunomodulatory mechanisms to
ensure long-lived infections in mammalian hosts. To manipulate mammalian immune …