Red blood cells (RBCs) are a specialised organ that enabled the evolution of multicellular
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …

Although blood transfusion is a lifesaving therapy for some patients, transfusion has been
named 1 of the top 5 overused procedures in US hospitals. As unnecessary transfusions …

Introduction Autologous salvaged blood, commonly referred to as “cell saver” or “cell
salvage” blood, is an important method of blood conservation. Understanding the …

Almost 150 years after the first autologous blood transfusion was reported, intraoperative
blood salvage has become an important method of blood conservation. The primary goal of …

BACKGROUND Clinical trials have shown that longer red blood cell (RBC) storage duration
does not worsen outcomes; however, these studies included few RBCs near the end of the …

Patient blood management is an increasingly used term to describe an evidence-based,
multidisciplinary approach to optimising the care of patients who might need transfusion. It …

BACKGROUND: Stored red blood cells (RBCs) are deficient in 2, 3-diphosphoglycerate (2, 3-
DPG), but it is unclear how autologous salvaged blood (ASB) compares with stored blood …

BACKGROUND Prolonged storage of red blood cells (RBCs) leads to storage lesions, which
may impair clinical outcomes after transfusion. A hallmark of storage lesions is progressive …

Red blood cell (RBC) transfusion is one of the most common therapeutic procedures in
modern medicine. Although frequently lifesaving, it often has deleterious side effects. RBC …

Red blood cells (RBC) in two-photon excited fluorescence (TPEF) microscopy usually
appear as dark disks because of their low fluorescent signal. Here we use 15fs 800nm …