We have published extensively on the neurogenetics of brain reward systems with reference
to the genes related to dopaminergic function in particular. In 1996, we coined “Reward …

Executive function entails the interplay of a group of cognitive processes enabling the
individual to anticipate consequences, attain self-control, and undertake appropriate goal …

Differential DNA methylation has been suggested to contribute to differential activity of
alleles C and T and thereby to genetic associations between the C/T (102) polymorphism in …

Twin and family studies reveal a significant genetic contribution to the risk of smoking
initiation and progression (SI/P), nicotine dependence (ND), and smoking cessation (SC) …

High levels of impulsivity can increase the vulnerability for development of alcohol
dependence. Moreover, impulsivity is considered to be a predictor of poor treatment …

In childhood and adolescence, overt antisocial and aggressive manifestations are typically
diagnosed as conduct disorder (CD). Given that the emerging research has pointed to the …

Evidence suggests an association between obesity and oxidative stress caused by
superoxide production. Since the dismutation of superoxide is catalyzed by superoxide …

Objectives Smoking is a major cause of death and often initiates in adolescence. Mutations
in CYP2A6 slow metabolism of nicotine to cotinine. Haploinsufficiency in adults is …

Pathological gambling (PG) has become a growing public health problem in many countries
around the world. PG is an impulse control disorder and its behavior and psychopathology …

PURPOSE AND METHODS: Cognitive behavior therapy (CBT) constitutes the basis of
smoking cessation programs. Quitting rates are usually increased by the concomitant use of …