An overview of drug resistance in protozoal diseases
R Capela, R Moreira, F Lopes - International journal of molecular …, 2019 - mdpi.com
Protozoan diseases continue to be a worldwide social and economic health problem.
Increased drug resistance, emerging cross resistance, and lack of new drugs with novel …
Increased drug resistance, emerging cross resistance, and lack of new drugs with novel …
Chemotherapy of leishmaniasis: present challenges
Cutaneous and visceral leishmaniasis are amongst the most devastating infectious diseases
of our time, affecting millions of people worldwide. The treatment of these serious diseases …
of our time, affecting millions of people worldwide. The treatment of these serious diseases …
Leishmania–macrophage interactions: Insights into the redox biology
Leishmaniasis is a neglected tropical disease that affects about 350 million individuals
worldwide. The protozoan parasite has a relatively simple life cycle with two principal …
worldwide. The protozoan parasite has a relatively simple life cycle with two principal …
Treatment of cutaneous leishmaniasis and insights into species-specific responses: a narrative review
RK Madusanka, H Silva, ND Karunaweera - Infectious diseases and …, 2022 - Springer
Cutaneous leishmaniasis (CL) is a complex skin infection that has imposed a heavy burden
on many developing countries and is caused by more than 20 Leishmania species. This …
on many developing countries and is caused by more than 20 Leishmania species. This …
Therapeutic advances in the topical treatment of cutaneous leishmaniasis: A review
M Azim, SA Khan, S Ullah, S Ullah… - PLoS neglected tropical …, 2021 - journals.plos.org
Cutaneous leishmaniasis has been endemic since decades. Millions of cases are reported
worldwide specially in developing and underdeveloped countries. There are 2 major types …
worldwide specially in developing and underdeveloped countries. There are 2 major types …
Repurposing as a strategy for the discovery of new anti-leishmanials: the-state-of-the-art
RL Charlton, B Rossi-Bergmann, PW Denny, PG Steel - Parasitology, 2018 - cambridge.org
Leishmaniasis is a vector-borne neglected tropical disease caused by protozoan parasites
of the genus Leishmania for which there is a paucity of effective viable non-toxic drugs …
of the genus Leishmania for which there is a paucity of effective viable non-toxic drugs …
Leishmaniasis and various immunotherapeutic approaches
Leishmaniasis is a vector-borne infectious disease caused by multiple Leishmania (L.)
species with diverse clinical manifestations. There is currently no vaccine against any form …
species with diverse clinical manifestations. There is currently no vaccine against any form …
Immunotherapy and immunochemotherapy in visceral leishmaniasis: promising treatments for this neglected disease
BM Roatt, RDO Aguiar-Soares, W Coura-Vital… - Frontiers in …, 2014 - frontiersin.org
Leishmaniasis has several clinical forms: self-healing or chronic cutaneous leishmaniasis or
post-kala-azar dermal leishmaniasis; mucosal leishmaniasis; visceral leishmaniasis (VL) …
post-kala-azar dermal leishmaniasis; mucosal leishmaniasis; visceral leishmaniasis (VL) …
Paromomycin Affects Translation and Vesicle-Mediated Trafficking as Revealed by Proteomics of Paromomycin –Susceptible –Resistant Leishmania donovani
B Chawla, A Jhingran, A Panigrahi, KD Stuart… - PloS one, 2011 - journals.plos.org
Leishmania donovani is a protozoan parasite that causes visceral leishmaniasis (VL) and is
responsible for significant mortality and morbidity. Increasing resistance towards antimonial …
responsible for significant mortality and morbidity. Increasing resistance towards antimonial …
[HTML][HTML] Genomic and transcriptomic alterations in Leishmania donovani lines experimentally resistant to antileishmanial drugs
A Rastrojo, R García-Hernández, P Vargas… - International Journal for …, 2018 - Elsevier
Leishmaniasis is a serious medical issue in many countries around the World, but it remains
largely neglected in terms of research investment for developing new control and treatment …
largely neglected in terms of research investment for developing new control and treatment …