Skeletal muscle mass increases during postnatal development through a process of
hypertrophy, ie enlargement of individual muscle fibers, and a similar process may be …

Sarcopenia, the age-related loss of muscle mass and function, imposes a dramatic burden
on individuals and society. The development of preventive and therapeutic strategies …

Societies are progressively aging, with the oldest old (ie., those aged> 80–85 years) being
the most rapidly expanding population segment. However, advanced aging comes at a …

The largest mammalian cells are the muscle fibers, and they have multiple nuclei to support
their large cytoplasmic volumes. During hypertrophic growth, new myonuclei are recruited …

Muscle loss during aging and disuse is a highly prevalent and disabling condition, but
knowledge about cellular pathways mediating muscle atrophy is still limited. Given the …

Effects of previous strength training can be long-lived, even after prolonged subsequent
inactivity, and retraining is facilitated by a previous training episode. Traditionally, such …

Mammalian skeletal muscles are composed of a variety of highly specialized fibers whose
selective recruitment allows muscles to fulfill their diverse functional tasks. In addition …

Memory is a process in which information is encoded, stored, and retrieved. For vertebrates,
the modern view has been that it occurs only in the brain. This review describes a cellular …

Neuromuscular disorders are a heterogeneous group of acquired or hereditary conditions
that affect striated muscle function. The resulting decrease in muscle strength and motility …

MicroRNAs (miRNAs) are small, noncoding RNAs that regulate gene expression and, in
cancers, are often packaged within secreted microvesicles. The cachexia syndrome is a …