Cerebral dysfunctions caused by sepsis during ageing

T Manabe, MT Heneka - Nature Reviews Immunology, 2022 - nature.com
Systemic inflammation elicited by sepsis can induce an acute cerebral dysfunction known as
sepsis-associated encephalopathy (SAE). Recent evidence suggests that SAE is common …

Unhealthy gut, unhealthy brain: The role of the intestinal microbiota in neurodegenerative diseases

LJ Spielman, DL Gibson, A Klegeris - Neurochemistry international, 2018 - Elsevier
The number of bacterial cells living within the human body is approximately equal to, or
greater than, the total number of human cells. This dynamic population of microorganisms …

Vagus nerve stimulation in brain diseases: Therapeutic applications and biological mechanisms

Y Wang, G Zhan, Z Cai, B Jiao, Y Zhao, S Li… - … & Biobehavioral Reviews, 2021 - Elsevier
Brain diseases, including neurodegenerative, cerebrovascular and neuropsychiatric
diseases, have posed a deleterious threat to human health and brought a great burden to …

Vagus nerve and vagus nerve stimulation, a comprehensive review: part I

H Yuan, SD Silberstein - Headache: The Journal of Head and …, 2016 - Wiley Online Library
The vagus nerve (VN), the “great wondering protector” of the body, comprises an intricate
neuro‐endocrine‐immune network that maintains homeostasis. With reciprocal neural …

Vagus nerve stimulation

RH Howland - Current behavioral neuroscience reports, 2014 - Springer
The vagus nerve is a major component of the autonomic nervous system, has an important
role in the regulation of metabolic homeostasis, and plays a key role in the neuro-endocrine …

Parametric characterization of neural activity in the locus coeruleus in response to vagus nerve stimulation

DR Hulsey, JR Riley, KW Loerwald… - Experimental …, 2017 - Elsevier
Vagus nerve stimulation (VNS) has emerged as a therapy to treat a wide range of
neurological disorders, including epilepsy, depression, stroke, and tinnitus. Activation of …

Surgically implanted and non‐invasive vagus nerve stimulation: a review of efficacy, safety and tolerability

E Ben‐Menachem, D Revesz, BJ Simon… - European journal of …, 2015 - Wiley Online Library
Vagus nerve stimulation (VNS) is effective in refractory epilepsy and depression and is
being investigated in heart failure, headache, gastric motility disorders and asthma. The first …

Treating depression with transcutaneous auricular vagus nerve stimulation: state of the art and future perspectives

J Kong, J Fang, J Park, S Li, P Rong - Frontiers in psychiatry, 2018 - frontiersin.org
Depression is a highly prevalent disorder, and its treatment is far from satisfactory. There is
an urgent need to develop a new treatment for depression. Although still at its early stage …

Strategies for precision vagus neuromodulation

U Ahmed, YC Chang, S Zafeiropoulos… - Bioelectronic …, 2022 - Springer
The vagus nerve is involved in the autonomic regulation of physiological homeostasis,
through vast innervation of cervical, thoracic and abdominal visceral organs. Stimulation of …

2015 ACVIM small animal consensus statement on seizure management in dogs

M Podell, HA Volk, M Berendt… - Journal of Veterinary …, 2016 - Wiley Online Library
This report represents a scientific and working clinical consensus statement on seizure
management in dogs based on current literature and clinical expertise. The goal was to …