Monitoring and measuring autophagy
SR Yoshii, N Mizushima - International journal of molecular sciences, 2017 - mdpi.com
Autophagy is a cytoplasmic degradation system, which is important for starvation adaptation
and cellular quality control. Recent advances in understanding autophagy highlight its …
and cellular quality control. Recent advances in understanding autophagy highlight its …
Autophagy in the eye: development, degeneration, and aging
P Boya, L Esteban-Martínez, A Serrano-Puebla… - Progress in retinal and …, 2016 - Elsevier
Autophagy is a catabolic pathway that promotes the degradation and recycling of cellular
components. Proteins, lipids, and even whole organelles are engulfed in autophagosomes …
components. Proteins, lipids, and even whole organelles are engulfed in autophagosomes …
[HTML][HTML] Nilotinib restores memory function by preventing dopaminergic neuron degeneration in a mouse model of Alzheimer's Disease
What happens precociously to the brain destined to develop Alzheimer's Disease (AD) still
remains to be elucidated and this is one reason why effective AD treatments are missing …
remains to be elucidated and this is one reason why effective AD treatments are missing …
TFEB biology and agonists at a glance
M Chen, Y Dai, S Liu, Y Fan, Z Ding, D Li - Cells, 2021 - mdpi.com
Autophagy is a critical regulator of cellular survival, differentiation, development, and
homeostasis, dysregulation of which is associated with diverse diseases including cancer …
homeostasis, dysregulation of which is associated with diverse diseases including cancer …
β-Cell Autophagy in Diabetes Pathogenesis
MR Marasco, AK Linnemann - Endocrinology, 2018 - academic.oup.com
Nearly 100 years have passed since Frederick Banting and Charles Best first discovered
and purified insulin. Their discovery and subsequent improvements revolutionized the …
and purified insulin. Their discovery and subsequent improvements revolutionized the …
Methods for measuring autophagy in mice
M Moulis, C Vindis - Cells, 2017 - mdpi.com
Autophagy is a dynamic intracellular process that mediates the degradation of damaged
cytoplasmic components by the lysosome. This process plays important roles in maintaining …
cytoplasmic components by the lysosome. This process plays important roles in maintaining …
The temporal pattern, flux, and function of autophagy in spinal cord injury
Previous studies have indicated that autophagy plays a critical role in spinal cord injury
(SCI), including traumatic spinal cord injury (TSCI) and ischemia-reperfusion spinal cord …
(SCI), including traumatic spinal cord injury (TSCI) and ischemia-reperfusion spinal cord …
Neuronal death after perinatal cerebral hypoxia-ischemia: Focus on autophagy—mediated cell death
C Descloux, V Ginet, PGH Clarke, J Puyal… - International Journal of …, 2015 - Elsevier
Neonatal hypoxic-ischemic encephalopathy is a critical cerebral event occurring around
birth with high mortality and neurological morbidity associated with long-term invalidating …
birth with high mortality and neurological morbidity associated with long-term invalidating …
Acidic nanoparticles protect against α‐synuclein‐induced neurodegeneration through the restoration of lysosomal function
ML Arotcarena, FN Soria, A Cunha, E Doudnikoff… - Aging …, 2022 - Wiley Online Library
Parkinson's disease (PD) is an age‐related neurodegenerative disorder characterized by
the loss of dopaminergic neurons in the substantia nigra, associated with the accumulation …
the loss of dopaminergic neurons in the substantia nigra, associated with the accumulation …
PP2C phosphatases Ptc1 and Ptc2 dephosphorylate PGK1 to regulate autophagy and aflatoxin synthesis in the pathogenic fungus Aspergillus flavus
Z Zhu, M Yang, G Yang, B Zhang, X Cao, J Yuan, F Ge… - Mbio, 2023 - Am Soc Microbiol
Reversible phosphorylation by protein kinases and phosphatases plays a central role in
regulating cellular processes. However, knowledge of the functions of protein phosphatase …
regulating cellular processes. However, knowledge of the functions of protein phosphatase …