Viral hijacking of cellular metabolism

SK Thaker, J Ch'ng, HR Christofk - BMC biology, 2019 - Springer
This review discusses the current state of the viral metabolism field and gaps in knowledge
that will be important for future studies to investigate. We discuss metabolic rewiring caused …

[HTML][HTML] Viral activation of cellular metabolism

EL Sanchez, M Lagunoff - Virology, 2015 - Elsevier
To ensure optimal environments for their replication and spread, viruses have evolved to
alter many host cell pathways. In the last decade, metabolomic studies have shown that …

How viral and intracellular bacterial pathogens reprogram the metabolism of host cells to allow their intracellular replication

W Eisenreich, T Rudel, J Heesemann… - Frontiers in cellular and …, 2019 - frontiersin.org
Viruses and intracellular bacterial pathogens (IBPs) have in common the need of suitable
host cells for efficient replication and proliferation during infection. In human infections, the …

The role of Epstein–Barr virus in nasopharyngeal carcinoma

ZY Su, PY Siak, CO Leong, SC Cheah - Frontiers in Microbiology, 2023 - frontiersin.org
Nasopharyngeal carcinoma (NPC) is a metastasis-prone malignancy closely associated
with the Epstein–Barr virus (EBV). Despite ubiquitous infection of EBV worldwide, NPC …

Virus infections and host metabolism—can we manage the interactions?

D Sumbria, E Berber, M Mathayan… - Frontiers in …, 2021 - frontiersin.org
When viruses infect cells, they almost invariably cause metabolic changes in the infected
cell as well as in several host cell types that react to the infection. Such metabolic changes …

Dengue virus induces and requires glycolysis for optimal replication

KA Fontaine, EL Sanchez, R Camarda… - Journal of …, 2015 - Am Soc Microbiol
Viruses rely on host cellular metabolism to provide the energy and biosynthetic building
blocks required for their replication. Dengue virus (DENV), a member of the Flaviviridae …

Hijacking the supplies: metabolism as a novel facet of virus-host interaction

KA Mayer, J Stöckl, GJ Zlabinger… - Frontiers in …, 2019 - frontiersin.org
Viral replication is a process that involves an extremely high turnover of cellular molecules.
Since viruses depend on the host cell to obtain the macromolecules needed for their proper …

[HTML][HTML] Targeting CPT1A-mediated fatty acid oxidation sensitizes nasopharyngeal carcinoma to radiation therapy

Z Tan, L Xiao, M Tang, F Bai, J Li, L Li, F Shi, N Li… - Theranostics, 2018 - ncbi.nlm.nih.gov
Nasopharyngeal carcinoma (NPC) has a particularly high prevalence in southern China,
southeastern Asia and northern Africa. Radiation resistance remains a serious obstacle to …

[HTML][HTML] Translational genomics of nasopharyngeal cancer

CM Tsang, VWY Lui, JP Bruce, TJ Pugh… - Seminars in cancer biology, 2020 - Elsevier
Nasopharyngeal carcinoma (NPC), also named the Cantonese cancer, is a unique cancer
with strong etiological association with infection of the Epstein-Barr virus (EBV). With …

Molecular mechanisms of EBV-driven cell cycle progression and oncogenesis

H Yin, J Qu, Q Peng, R Gan - Medical microbiology and immunology, 2019 - Springer
The early stage of oncogenesis is linked to the disorder of the cell cycle. Abnormal gene
expression often leads to cell cycle disorders, resulting in malignant transformation of …