The pathogenesis and clinical features of diabetic cardiomyopathy have been well-studied
in the past decade, but effective approaches to prevent and treat this disease are limited …

Patients with type 2 diabetes mellitus (T2DM) are at high risk for macrovascular
complications, which represent the major cause of mortality. Despite effective treatment of …

Objectives: This study evaluated the associations of obesity and cardiometabolic traits with
incident heart failure with preserved versus reduced ejection fraction (HFpEF vs. HFrEF) …

Oxidative stress occurs whenever the release of reactive oxygen species (ROS) exceeds
endogenous antioxidant capacity. In this paper, we review the specific role of several …

Background Purpose: to establish if exercise training improves clinical outcomes in people
with metabolic syndrome (MetS). Registered with PROSPERO international prospective …

In recent years, type 2 diabetes mellitus has evolved as a rapidly increasing epidemic that
parallels the increased prevalence of obesity and which markedly increases the risk of …

Diabetic cardiomyopathy (DCM) is a cardiac dysfunction which affects approximately 12% of
diabetic patients, leading to overt heart failure and death. However, there is not an efficient …

Accumulating evidence points to the existence of an inflammatory‐metabolic phenotype of
heart failure with a preserved ejection fraction (HFpEF), which is characterized by …

Diabetes mellitus increases the risk of heart failure independent of co-existing hypertension
and coronary artery disease. Although several molecular mechanisms for the development …

Aims Diastolic dysfunction (DD) is frequent in the general population; however, the
assessment of diastolic function remains challenging. We aimed to evaluate the impact of …