Natural products remain a crucial source of drug discovery for accessible and affordable
solutions for healthy aging. Centella asiatica (L.) Urb.(CA) is an important medicinal plant …

Formation of oxidative stress in dermal fibroblasts plays crucial roles in aging processes of
skin. The use of phytochemicals that can promote capacity of fibroblasts to combat oxidative …

Diabetes mellitus (DM) is a metabolic disease characterized by chronic hyperglycemia and
impaired islet secretion that places a heavy burden on the global health care system due to …

Centell-S is a water-soluble extract of Centella asiatica containing more than 80% w/w
triterpenoid glycosides. Madecassoside and asiaticoside are two major components of the …

Background Dysregulation of glucose and glycogen metabolism are crucial mechanisms
implicated in type 2 diabetes mellitus (T2DM). Centella asiatica (L.) Urban (Apiaceae) has …

The estrogenic impact of Bisphenol-A (BPA), a widely recognized endocrine disruptor,
causes disruption of pancreatic β-cell function through estrogen receptors (ERs). While …

The incidence and severity of diabetes mellitus is increasing worldwide, presenting a
significant burden to society both in economic terms and overall well-being. Fortunately, time …

Introduction. Uncontrolled diabetes mellitus (DM) is related to skin disorders, particularly dry
skin. Pathogenesis of dry skin in type 2 diabetes mellitus (T2DM) rises from the chronic …

Centella asiatica is claimed to have a neuroprotective effect; however, its ability to protect
the cerebrum against damage in diabetes has never been identified. The aims were to …

Bisphenol-A (BPA) is widely used in food packaging and household products, leading to
daily human exposure and potential health risks including metabolic diseases like type 2 …