Procreation is essential for survival of species. Not surprisingly, complex neuronal networks
have evolved to mediate the diverse internal and external environmental inputs that regulate …

The concept that different systems control episodic and surge secretion of gonadotropin‐
releasing hormone (GnRH) was well established by the time that GnRH was identified and …

Essential Reproduction provides an accessible account of the fundamentals of reproduction
within the context of cutting-edge knowledge and examples of its application. The eighth …

Increasing evidence accumulated during the past two decades has demonstrated that the
then-novel kisspeptin, which was discovered in 2001, the known neuropeptides neurokinin …

Estrogen produced by ovarian follicles plays a key role in the central mechanisms
controlling reproduction via regulation of gonadotropin-releasing hormone (GnRH) release …

Adipose tissue plays a dynamic role in whole-body energy homeostasis by acting as an
endocrine organ. Collective evidence indicates a strong link between neural influences and …

Gonadotropin-releasing hormone (GnRH) secretion has two modes of release in
mammalian species; the surge mode and the pulse mode. The surge mode, which is …

Pubertal onset is thought to be timed by an increase in pulsatile gonadotropin-releasing
hormone (GnRH)/gonadotropin secretion in mammals. The underlying mechanism of …

Kisspeptins, encoded by the Kiss1 gene, and their canonical receptor, GPR54 (also termed
Kiss1R), are unanimously recognised as essential regulators of puberty onset and …

This study aims to determine the epigenetic mechanism regulating Kiss1 gene expression in
the anteroventral periventricular nucleus (AVPV) to understand the mechanism underlying …