Liver metastases

DI Tsilimigras, P Brodt, PA Clavien… - Nature reviews Disease …, 2021 - nature.com
Liver metastases are commonly detected in a range of malignancies including colorectal
cancer (CRC), pancreatic cancer, melanoma, lung cancer and breast cancer, although CRC …

MRI-guided adaptive radiotherapy for liver tumours: visualising the future

JS Witt, SA Rosenberg, MF Bassetti - The Lancet Oncology, 2020 - thelancet.com
MRI-guided radiotherapy is a novel and rapidly evolving technology that might enhance the
risk–benefit ratio. Through direct visualisation of the tumour and the nearby healthy tissues …

Impact of cirrhosis in patients undergoing laparoscopic liver resection in a nationwide multicentre survey

C Hobeika, D Fuks, F Cauchy, C Goumard… - Journal of British …, 2020 - academic.oup.com
Background The aim was to analyse the impact of cirrhosis on short-term outcomes after
laparoscopic liver resection (LLR) in a multicentre national cohort study. Methods This …

Influence of cytokines, circulating markers and growth factors on liver regeneration and post-hepatectomy liver failure: a systematic review and meta-analysis

A Murtha-Lemekhova, J Fuchs, O Ghamarnejad… - Scientific reports, 2021 - nature.com
The pathophysiology of post-hepatectomy liver failure is not entirely understood but is rooted
in the disruption of normal hepatocyte regeneration and homeostasis. Current investigations …

[HTML][HTML] Complications after liver surgery: a benchmark analysis

F Bagante, A Ruzzenente, EW Beal, T Campagnaro… - Hpb, 2019 - Elsevier
Background The best achievable short-term outcomes after liver surgery have not been
identified. Several factors may influence the post-operative course of patients undergoing …

Synergistic impact of alpha-fetoprotein and tumor burden on long-term outcomes following curative-intent resection of hepatocellular carcinoma

DI Tsilimigras, JM Hyer, A Diaz, F Bagante, F Ratti… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) tumor burden score (TBS) and α-
fetoprotein (AFP) have been considered important predictors of outcomes among patients …

Intrahepatic fibrin (ogen) deposition drives liver regeneration after partial hepatectomy in mice and humans

D Groeneveld, D Pereyra, Z Veldhuis… - Blood, The Journal …, 2019 - ashpublications.org
Platelets play a pivotal role in stimulating liver regeneration after partial hepatectomy in
rodents and humans. Liver regeneration in rodents is delayed when platelets are inhibited …

Prognostic utility of albumin‐bilirubin grade for short‐and long‐term outcomes following hepatic resection for intrahepatic cholangiocarcinoma: a multi‐institutional …

DI Tsilimigras, JM Hyer, D Moris… - Journal of surgical …, 2019 - Wiley Online Library
Background The objective of the current study was to define the impact of albumin‐bilirubin
(ALBI) grade on short‐as well as long‐term outcomes among patients with intrahepatic …

Treatment patterns for hepatocellular carcinoma in patients with Child–Pugh class B and their impact on survival: A Korean nationwide registry study

D Jeon, GW Song, HC Lee, JH Shim - Liver International, 2022 - Wiley Online Library
Abstract Background and Aims There are no established practice guidelines for treating
hepatocellular carcinoma (HCC) in patients with Child–Turcotte–Pugh (CTP) class B liver …

State-of-the-art surgery for hepatocellular carcinoma

N Machairas, DI Tsilimigras, TM Pawlik - Langenbeck's archives of surgery, 2021 - Springer
Background Hepatocellular carcinoma (HCC) is the most commonly diagnosed primary liver
tumor with an increasing incidence worldwide. Management of patients with HCC is largely …