Thiazole: A promising heterocycle for the development of potent CNS active agents
Thiazole is a valuable scaffold in the field of medicinal chemistry and has accounted to
display a variety of biological activities. Thiazole and its derivatives have attracted …
display a variety of biological activities. Thiazole and its derivatives have attracted …
Adenosine receptor antagonists: Recent advances and therapeutic perspective
Adenosine is an endogenous purine-based nucleoside expressed nearly in all body tissues.
It regulates various body functions by activating four G-protein coupled receptors, A 1, A 2A …
It regulates various body functions by activating four G-protein coupled receptors, A 1, A 2A …
Role of rutin nanoemulsion in ameliorating oxidative stress: pharmacokinetic and pharmacodynamics studies
Parkinson's disease is caused due to free radical generation in dopamine neurons leading
to oxidative stress induced damage. The aim of this work was to ameliorate the free radical …
to oxidative stress induced damage. The aim of this work was to ameliorate the free radical …
History and Perspectives of A2A Adenosine Receptor Antagonists as Potential Therapeutic Agents
D Preti, PG Baraldi, AR Moorman… - Medicinal research …, 2015 - Wiley Online Library
Growing evidence emphasizes that the purine nucleoside adenosine plays an active role as
a local regulator in different pathologies. Adenosine is a ubiquitous nucleoside involved in …
a local regulator in different pathologies. Adenosine is a ubiquitous nucleoside involved in …
Haloperidol‐induced catalepsy as an animal model for parkinsonism: A systematic review of experimental studies
I Waku, MS Magalhaes, CO Alves… - European Journal of …, 2021 - Wiley Online Library
Several useful animal models for parkinsonism have been developed so far. Haloperidol‐
induced catalepsy is often used as a rodent model for the study of motor impairments …
induced catalepsy is often used as a rodent model for the study of motor impairments …
Copper-Catalyzed Coupling Cyclization of gem-Difluoroalkenes with Activated Methylene Carbonyl Compounds: Facile Domino Access to Polysubstituted Furans
X Zhang, W Dai, W Wu, S Cao - Organic letters, 2015 - ACS Publications
A novel and efficient CuI-catalyzed synthesis of 2, 3, 5-trisubstituted furans was developed
via coupling cyclization of gem-difluoroalkenes with active methylene carbonyl compounds …
via coupling cyclization of gem-difluoroalkenes with active methylene carbonyl compounds …
Synthesis of Tetrasubstituted Furans through One-Pot Formal [3+ 2] Cycloaddition Utilizing [1, 2]-Phospha-Brook Rearrangement
A Kondoh, K Aita, S Ishikawa, M Terada - Organic letters, 2020 - ACS Publications
An efficient method for the synthesis of tetrasubstituted furans was developed by utilizing the
[1, 2]-phospha-Brook rearrangement under Brønsted base catalysis. The two-step one-pot …
[1, 2]-phospha-Brook rearrangement under Brønsted base catalysis. The two-step one-pot …
[3+ 2] Cycloaddition of α-Aryl-α-diazoacetates with Terminal Alkynes via the Cooperative Catalysis of Palladium and Acid
H Guo, S Zhang, X Yu, X Feng, Y Yamamoto… - ACS Catalysis, 2021 - ACS Publications
Palladium and acid cooperative catalysis is presented as a strategy for the [3+ 2]
cycloaddition of acceptor/donor-type diazo compounds with terminal alkynes. The [3+ 2] …
cycloaddition of acceptor/donor-type diazo compounds with terminal alkynes. The [3+ 2] …
FeCl 3 or MeSO 3 H-promoted multicomponent reactions for facile synthesis of structurally diverse furan analogues
X Chang, X Zhang, Z Chen - Organic & biomolecular chemistry, 2018 - pubs.rsc.org
An intriguing conversion of arylglyoxal, cyclic dicarbonyl compounds and phenols to diverse
furan analogues under FeCl3 or MeSO3H catalysis is reported. Utilizing this synthetic …
furan analogues under FeCl3 or MeSO3H catalysis is reported. Utilizing this synthetic …
Solvent-Free DABCO-mediated [3+ 2] cycloadditions of donor–acceptor cyclopropanes with aldehydes: strategy for synthesis of fully substituted furans
J Liu, W Ye, X Qing, C Wang - The Journal of Organic Chemistry, 2016 - ACS Publications
DABCO-mediated [3+ 2] cycloadditions of donor–acceptor cyclopropanes with aldehydes
under solvent-free conditions have been developed for the preparation of fully substituted …
under solvent-free conditions have been developed for the preparation of fully substituted …