Wnt signalling in stem cells and cancer
The canonical Wnt cascade has emerged as a critical regulator of stem cells. In many
tissues, activation of Wnt signalling has also been associated with cancer. This has raised …
tissues, activation of Wnt signalling has also been associated with cancer. This has raised …
Follicular dendritic cell sarcoma: clinicopathologic analysis of 17 cases suggesting a malignant potential higher than currently recognized
JKC Chan, CDM Fletcher, SJ Nayler, K Cooper - Cancer, 1997 - Wiley Online Library
BACKGROUND The goal of this study was to characterize the clinicopathologic features of
follicular dendritic cell sarcoma, a very uncommon neoplasm. METHODS The 17 cases were …
follicular dendritic cell sarcoma, a very uncommon neoplasm. METHODS The 17 cases were …
Synaptophysin: a marker protein for neuroendocrine cells and neoplasms.
B Wiedenmann, WW Franke, C Kuhn… - Proceedings of the …, 1986 - National Acad Sciences
Synaptophysin is an integral membrane glycoprotein (Mr 38,000) that occurs in presynaptic
vesicles of neurons and in similar vesicles of the adrenal medulla. By using a monoclonal …
vesicles of neurons and in similar vesicles of the adrenal medulla. By using a monoclonal …
Plakoglobin: a protein common to different kinds of intercellular adhering junctions
We have established, by means of a monoclonal antibody and a cDNA clone, that a
desmosomal polypeptide of M, 83,000 also occurs at the plaques of other types of adhering …
desmosomal polypeptide of M, 83,000 also occurs at the plaques of other types of adhering …
The area composita of adhering junctions connecting heart muscle cells of vertebrates. I. Molecular definition in intercalated disks of cardiomyocytes by …
WW Franke, CM Borrmann, C Grund… - European journal of cell …, 2006 - Elsevier
Among sarcomeric muscles the cardiac muscle cells are unique by, inter alia, a systemic
and extended cell–cell contact structure, the intercalated disk (ID), comprising frequent and …
and extended cell–cell contact structure, the intercalated disk (ID), comprising frequent and …
Structure and function of desmosomes
B Holthöfer, R Windoffer, S Troyanovsky… - International review of …, 2007 - Elsevier
Desmosomes are prominent adhesion sites that are tightly associated with the cytoplasmic
intermediate filament cytoskeleton providing mechanical stability in epithelia and also in …
intermediate filament cytoskeleton providing mechanical stability in epithelia and also in …
Breaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles …
EA Bornslaeger, CM Corcoran… - The Journal of cell …, 1996 - rupress.org
The desmosomal plaque protein desmoplakin (DP), located at the juncture between the
intermediate filament (IF) network and the cytoplasmic tails of the transmembrane …
intermediate filament (IF) network and the cytoplasmic tails of the transmembrane …
Structure of the human desmoplakins. Implications for function in the desmosomal plaque.
KJ Green, DA Parry, PM Steinert, ML Virata… - Journal of Biological …, 1990 - ASBMB
Desmoplakins (DPs) I and II are two major related proteins located in the innermost portion
of the desmosomal plaque where it is thought they may play a role in attaching intermediate …
of the desmosomal plaque where it is thought they may play a role in attaching intermediate …
Discovering the molecular components of intercellular junctions—a historical view
WW Franke - Cold Spring Harbor perspectives in biology, 2009 - cshperspectives.cshlp.org
The organization of metazoa is based on the formation of tissues and on tissue-typical
functions and these in turn are based on cell–cell connecting structures. In vertebrates, four …
functions and these in turn are based on cell–cell connecting structures. In vertebrates, four …
Symplekin, a novel type of tight junction plaque protein.
BH Keon, S Schäfer, C Kuhn, C Grund… - The Journal of cell …, 1996 - rupress.org
Using a monoclonal antibody we have identified and cDNA-cloned a novel type of protein
localized, by light and electron microscopy, to the plaque associated with the cytoplasmic …
localized, by light and electron microscopy, to the plaque associated with the cytoplasmic …