Aim: The “2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid
Hemorrhage” replaces the 2012 “Guidelines for the Management of Aneurysmal …

Background Aneurysmal subarachnoid hemorrhage is a life-threatening disease requiring
neurocritical care. Delayed cerebral ischemia is a well-known complication that contributes …

Background: Several clinical studies have indicated the efficacy of cilostazol, a selective
inhibitor of phosphodiesterase 3, in preventing cerebral vasospasm after aneurysmal …

Therapeutic hypothermia (TH) improves the neurological outcome in patients after cardiac
arrest and neonatal hypoxic brain injury. We studied the safety and feasibility of mild TH in …

BACKGROUND: Although targeted temperature management (TTM) may mitigate brain
injury for severe subarachnoid hemorrhage (SAH), rebound fever correlates with poor …

As a subtype of stroke, subarachnoid hemorrhage (SAH) has a notoriously high rate of
disability and mortality owing to the lack of effective intervention. Early brain injury (EBI) is …

Objective Therapeutic hypothermia improves the prognosis of patients with poor-grade
subarachnoid hemorrhage (SAH). We investigated the clinical and radiological effects of …

Objectives: Standard management strategies for lowering intracranial pressure (ICP) in
traumatic brain injury has been well-studied, but the use of lesser known interventions for …

We assessed the feasibility of therapeutic early and prolonged mild hypothermia (MH) in
patients with poor-grade subarachnoid hemorrhage (SAH). A retrospective pilot study was …

A bulk of evidence from animal models indicates that lowering temperature by a few degrees
can confer neuroprotection against ischemia. 1 In humans, targeted temperature …