Chalcone scaffolds, bioprecursors of flavonoids: Chemistry, bioactivities, and pharmacokinetics

M Rudrapal, J Khan, AAB Dukhyil, RMII Alarousy… - Molecules, 2021 - mdpi.com
Chalcones are secondary metabolites belonging to the flavonoid (C6-C3-C6 system) family
that are ubiquitous in edible and medicinal plants, and they are bioprecursors of plant …

[HTML][HTML] The antiviral and antimicrobial activities of licorice, a widely-used Chinese herb

L Wang, R Yang, B Yuan, Y Liu, C Liu - Acta pharmaceutica sinica B, 2015 - Elsevier
Licorice is a common herb which has been used in traditional Chinese medicine for
centuries. More than 20 triterpenoids and nearly 300 flavonoids have been isolated from …

Glycyrrhiza Genus: Enlightening Phytochemical Components for Pharmacological and Health‐Promoting Abilities

J Sharifi-Rad, C Quispe, J Herrera-Bravo… - Oxidative medicine …, 2021 - Wiley Online Library
The Glycyrrhiza genus, generally well‐known as licorice, is broadly used for food and
medicinal purposes around the globe. The genus encompasses a rich pool of bioactive …

A comprehensive review on the antiviral activities of chalcones

D Elkhalifa, I Al-Hashimi, AE Al Moustafa… - Journal of Drug …, 2021 - Taylor & Francis
Some viral outbreaks have plagued the world since antiquity, including the most recent
COVID-19 pandemic. The continuous spread and emergence of new viral diseases have …

The potential and action mechanism of polyphenols in the treatment of liver diseases

S Li, HY Tan, N Wang, F Cheung… - … medicine and cellular …, 2018 - Wiley Online Library
Liver disease, involving a wide range of liver pathologies from fatty liver, hepatitis, and
fibrosis to cirrhosis and hepatocellular carcinoma, is a serious health problem worldwide. In …

Therapeutic potential of flavonoids and their mechanism of action against microbial and viral infections—A review

A Ahmad, M Kaleem, Z Ahmed, H Shafiq - Food Research International, 2015 - Elsevier
Flavonoids are polyphenolic phytochemicals generally found in vegetables, fruits, flowers,
nuts, seeds, tea, honey and propolis. In the past plants containing these compounds have …

Role of flavonoids in plant interactions with the environment and against human pathogens—A review

M Khalid, M Bilal, DF Huang - Journal of integrative agriculture, 2019 - Elsevier
Flavonoids are widely-distributed polyphenolic secondary metabolites with diverse
biological activities in plants and benefit human health as protective dietary agents. They …

Phytochemicals from plant foods as potential source of antiviral agents: An overview

T Behl, G Rocchetti, S Chadha, G Zengin, S Bungau… - Pharmaceuticals, 2021 - mdpi.com
To date, the leading causes of mortality and morbidity worldwide include viral infections,
such as Ebola, influenza virus, acquired immunodeficiency syndrome (AIDS), severe acute …

[HTML][HTML] The potential of glycyrrhizin and licorice extract in combating COVID-19 and associated conditions

AA Gomaa, YA Abdel-Wadood - Phytomedicine plus, 2021 - Elsevier
Background Several recent studies have stated that glycyrrhizin and licorice extract are
present in most traditional Chinese medicine formulas used against SARS-CoV-2 in China …

Synthesis, reactions and application of chalcones: A systematic review

MA Shalaby, SA Rizk, AM Fahim - Organic & Biomolecular Chemistry, 2023 - pubs.rsc.org
Chalcones are a group of naturally occurring compounds that have biological effects that
include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone …