Noncanonical inheritance of phenotypic information by protein amyloids
M Eroglu, T Zocher, J McAuley, R Webster… - Nature Cell …, 2024 - nature.com
All known heritable phenotypic information in animals is transmitted by direct inheritance of
nucleic acids, their covalent modifications or histone modifications that modulate expression …
nucleic acids, their covalent modifications or histone modifications that modulate expression …
The idiosyncrasies of oocytes
JW Pek - Trends in Cell Biology, 2024 - cell.com
Animal oocytes face extreme challenges. They remain dormant in the body for long periods
of time. To support offspring development and health, they need to store genetic material …
of time. To support offspring development and health, they need to store genetic material …
Autophagy in reproduction and pregnancy-associated diseases
A Singh, ML Perez, O Kirsanov, E Padilla-Banks… - iScience, 2024 - cell.com
As advantageous as sexual reproduction is during progeny generation, it is also an
expensive and treacherous reproductive strategy. The viviparous eukaryote has evolved to …
expensive and treacherous reproductive strategy. The viviparous eukaryote has evolved to …
Protein research may hint at how human eggs survive for decades
C Szalinski - Proceedings of the National Academy of Sciences, 2024 - pnas.org
Human eggs, called oocytes, have a superpower: They can stay in the ovaries for decades,
from before a woman is born until she's over age 40. Most of our cells are constantly turning …
from before a woman is born until she's over age 40. Most of our cells are constantly turning …
Switching on lysosomes
D Adhikari, J Carroll - Elife, 2024 - elifesciences.org
Fertilization: Switching on lysosomes | eLife Skip to Content eLife logo eLife home page
Menu Home Magazine Community About Search Alerts Submit your research Search by …
Menu Home Magazine Community About Search Alerts Submit your research Search by …
ELVAs: The new 'super-organelles' of the oocyte
H Fulka - Lab Animal, 2024 - nature.com
Omne vivum ex ovo—Every living thing comes from an egg. However, keeping eggs healthy
and competent to form viable embryos is not an easy task for every organism. A recent paper …
and competent to form viable embryos is not an easy task for every organism. A recent paper …
PITHD1: An Endogenous Inhibitor of the 26S Proteasome During Cellular Dormancy
SJ Amann, K Dong, J Roehsner, D Krall… - bioRxiv, 2024 - biorxiv.org
Cellular dormancy represents a state of regulated growth arrest essential for diverse
biological processes, from reproduction to cancer progression. While mechanisms …
biological processes, from reproduction to cancer progression. While mechanisms …
Der Einsatz von „platelet-rich plasma “(PRP) bei reduzierter ovarieller Reserve und ovarieller Insuffizienz–Hoffnung oder ungerechtfertigter Hype?
M Murtinger, H Bralo, M Zech, B Wirleitner… - Gynäkologie in der …, 2024 - Springer
Prämature Ovarialinsuffizienz (POI) und reduzierte ovarielle Reserve (engl.„diminished
ovarian reserve “–kurz DOR) stellen–nicht zuletzt angesichts der immer späteren …
ovarian reserve “–kurz DOR) stellen–nicht zuletzt angesichts der immer späteren …
Endosomal-lysosomal organellar assembly (ELYSA) structures coordinate lysosomal degradation systems through mammalian oocyte-to-embryo transition
Mouse oocytes undergo drastic changes in organellar composition and their activities during
maturation from the germinal vesicle (GV) to meiosis II (MII) stage. After fertilization, the …
maturation from the germinal vesicle (GV) to meiosis II (MII) stage. After fertilization, the …
Aggregation of misfolded proteins in the sperm head is associated with decreased bovine pre-implantation embryonic development
E Anta Galvan - 2024 - minds.wisconsin.edu
While maternal contributions to embryogenesis are well-documented, the paternal role in
influencing post-fertilization events remains underexplored. This study investigates the …
influencing post-fertilization events remains underexplored. This study investigates the …