Deficits in brain function that are associated with aging and age-related diseases benefit
very little from currently available therapies, suggesting a better understanding of the …

Neurodegenerative diseases such as Parkinson's disease (PD), Alzheimer's disease (AD),
amyotrophic lateral sclerosis (ALS), and spinal muscular atrophy (SMA) are chronic …

Studies have shown that mesenchymal stem cell-derived exosomes can enhance neural
plasticity and improve cognitive impairment. The purpose of this study was to investigate the …

Plasticity of intrinsic neuronal excitability facilitates learning and memory across multiple
species, with aberrant modulation of this process being linked to the development of …

Extracellular beta‐amyloid (Aβ) accumulation and deposition is the main factor, which
causes synaptic loss and eventually cells death in Alzheimer's disease (AD). Memory loss …

With more than 80 subunits, potassium (K+) channels represent a group of ion channels
showing high degree of diversity and ubiquity. They play important role in the control of …

Ion channels activated around the subthreshold membrane potential determine the
likelihood of neuronal firing in response to synaptic inputs, a process described as intrinsic …

Autism spectrum disorder (ASD) is a common neuropsychiatric disorder, which is
characterized by impairment in social interaction and cognitive behaviors. However, there is …

Posttraumatic stress disorder (PTSD) is a debilitating mental condition occurring after a
tragedy or a traumatic experience, such as rape, assault, natural disasters, war, car or plane …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that causes memory
loss. Most AD researches have focused on neurodegeneration mechanisms. Considering …