Response assessment criteria for glioblastoma: practical adaptation and implementation in clinical trials of antiangiogenic therapy

OL Chinot, DR Macdonald, LE Abrey… - Current neurology and …, 2013 - Springer
Since 1990, the primary criteria used for assessing response to therapy in high-grade
gliomas were those developed by Macdonald and colleagues, which incorporated 2 …

Physiologic MRI for assessment of response to therapy and prognosis in glioblastoma

MS Shiroishi, JL Boxerman, WB Pope - Neuro-oncology, 2015 - academic.oup.com
Aside from bidimensional measurements from conventional contrast-enhanced MRI, there
are no validated or FDA-qualified imaging biomarkers for high-grade gliomas. However …

A specific miRNA signature in the peripheral blood of glioblastoma patients

P Roth, J Wischhusen, C Happold… - Journal of …, 2011 - Wiley Online Library
J. Neurochem.(2011) 118, 449–457. Abstract The prognosis of patients afflicted by
glioblastoma remains poor. Biomarkers for the disease would be desirable in order to allow …

Mean diffusional kurtosis in patients with glioma: initial results with a fast imaging method in a clinical setting

A Tietze, MB Hansen, L Østergaard… - American journal …, 2015 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Diffusional kurtosis imaging is an MR imaging technique
that provides microstructural information in biologic systems. Its application in clinical …

Diffusion weighted/tensor imaging, functional MRi and Perfusion weighted imaging in glioblastoma—foundations and future

GR Salama, LA Heier, P Patel, R Ramakrishna… - Frontiers in …, 2018 - frontiersin.org
In this article, we review the basics of diffusion tensor imaging and functional MRI, their
current utility in preoperative neurosurgical mapping, and their limitations. We also discuss …

Assessment of therapeutic response and treatment planning for brain tumors using metabolic and physiological MRI

SJ Nelson - NMR in Biomedicine, 2011 - Wiley Online Library
MRI is routinely used for diagnosis, treatment planning and assessment of response to
therapy for patients with glioma. Gliomas are spatially heterogeneous and infiltrative lesions …

Glioma grading using apparent diffusion coefficient map: application of histogram analysis based on automatic segmentation

J Lee, SH Choi, JH Kim, CH Sohn, S Lee… - NMR in …, 2014 - Wiley Online Library
The accurate diagnosis of glioma subtypes is critical for appropriate treatment, but
conventional histopathologic diagnosis often exhibits significant intra‐observer variability …

Immediate post-operative MRI suggestive of the site and timing of glioblastoma recurrence after gross total resection: a retrospective longitudinal preliminary study

T Smets, TM Lawson, C Grandin, A Jankovski… - European …, 2013 - Springer
Objectives To retrospectively identify morphological and physiological post-operative
magnetic resonance imaging (MRI) characteristics predictive of glioblastoma recurrences …

Residual low ADC and high FA at the resection margin correlate with poor chemoradiation response and overall survival in high-grade glioma patients

J Qu, L Qin, S Cheng, K Leung, X Li, H Li, J Dai… - European Journal of …, 2016 - Elsevier
Purpose We hypothesized that ADC and FA of enhancing tumor (ET) and/or non-enhancing
tumor (NT) adjacent to the operative resection margin before and during temozolomide …

[HTML][HTML] Advanced MR imaging methods for planning and monitoring radiation therapy in patients with high grade glioma

JM Lupo, SJ Nelson - Seminars in radiation oncology, 2014 - ncbi.nlm.nih.gov
This review explores how the integration of advanced imaging methods with high quality
anatomic images significantly improves the characterization, target definition, assessment of …