Abstract Toll-like receptor (TLR) 4 belongs to the TLR family of receptors inducing pro-
inflammatory responses to invading pathogens. TLR4 is activated by lipopolysaccharide …

Bronchial asthma is a complex heterogeneous airway disease, which has emerged as a
global health issue. A comprehensive understanding of the different molecular mechanisms …

Allergic asthma is a chronic and heterogeneous pulmonary disease in which platelets can
be activated in an IgE-mediated pathway and migrate to the airways via CCR3-dependent …

Our understanding on the immunological roles of pathogen recognition in innate immunity
has vastly increased over the past 20 years. Nucleotide-binding oligomerization domain …

Background: Accumulating evidence indicated the crucial role for interleukin 6 (IL-6)
signaling in the development of allergic asthma. Yet, the role of IL-6 signaling in toluene …

Over the past few years, ozone has been identified as a potential risk factor for exacerbating
asthma. However, few attempts have been made to prevent the progression of ozone …

Obese asthma is a form of refractory asthma with inflammation as the underlying
mechanism. The specific mechanism of action of anti-inflammatory growth differentiation …

Background and purpose Toluene diisocyanate (TDI)-induced asthma is characterized by
mixed inflammation dominated by neutrophils, and is refractory to steroid treatment …

Asthma is a respiratory disease characterized by heterogeneous chronic airway
inflammation. Activation of nucleotide-binding oligomerization domain-like receptor pyrin …

高血压和支气管哮喘分别是心血管系统和呼吸系统常见的慢性病. 基因易感性,
炎症机制以及不良生活方式等均可增加高血压和哮喘的发病风险. 近年来高血压合并哮喘在发病 …