Stimuli-responsive polymeric nanovaccines toward next-generation immunotherapy

L Mao, P Ma, X Luo, H Cheng, Z Wang, E Ye, XJ Loh… - ACS …, 2023 - ACS Publications
The development of nanovaccines that employ polymeric delivery carriers has garnered
substantial interest in therapeutic treatment of cancer and a variety of infectious diseases …

A state-of-the-art review on solid lipid nanoparticles as a nanovaccines delivery system

M Assefi, M Ataeinaeini, A Nazari, A Gholipour… - Journal of Drug Delivery …, 2023 - Elsevier
In the design of vaccine generation, significant attempts have been made to produce novel
vaccines and, as well, to increase the effectiveness of available vaccines versus particular …

Instructional materials that control cellular activity through synthetic Notch receptors

JC Lee, HJ Brien, BL Walton, ZM Eidman, S Toda… - Biomaterials, 2023 - Elsevier
The field of regenerative engineering relies primarily on the dual technical platforms of cell
selection/conditioning and biomaterial fabrication to support directed cell differentiation. As …

[HTML][HTML] Engineering customized nanovaccines for enhanced cancer immunotherapy

J Guo, C Liu, Z Qi, T Qiu, J Zhang, H Yang - Bioactive Materials, 2024 - Elsevier
Nanovaccines have gathered significant attention for their potential to elicit tumor-specific
immunological responses. Despite notable progress in tumor immunotherapy, nanovaccines …

Macro-microporous ZIF-8 MOF complexed with lysosomal pH-adjusting hexadecylsulfonylfluoride as tumor vaccine delivery systems for improving anti-tumor cellular …

Q Zuo, T Li, L Huang, Z Liu, W Xue - Biomaterials Science, 2023 - pubs.rsc.org
Tumor vaccine therapy, which can induce tumor antigen-specific cellular immune responses
to directly kill tumor cells, is considered to be one of the most promising tumor …

[HTML][HTML] Nanovaccines: an effective therapeutic approach for cancer therapy

S Gurunathan, P Thangaraj, L Wang, Q Cao… - Biomedicine & …, 2024 - Elsevier
Cancer vaccines hold considerable promise for the immunotherapy of solid tumors.
Nanomedicine offers several strategies for enhancing vaccine effectiveness. In particular …

Liposomal celecoxib combined with dendritic cell therapy enhances antitumor efficacy in melanoma

V Jahani, M Yazdani, A Badiee, MR Jaafari… - Journal of Controlled …, 2023 - Elsevier
Cancer vaccine efficacy is limited by the immunosuppressive nature of the tumor
microenvironment created by inflammation, immune inhibitory factors, and regulatory T cells …

Engineering endosomolytic nanocarriers of diverse morphologies using confined impingement jet mixing

HM Pagendarm, PT Stone, BR Kimmel, JJ Baljon… - Nanoscale, 2023 - pubs.rsc.org
The clinical translation of many biomolecular therapeutics has been hindered by
undesirable pharmacokinetic (PK) properties, inadequate membrane permeability, poor …

Boosting antigen-specific T cell activation with lipid-stabilized protein nanoaggregates

M Schlich, L D'Apice, F Lai, C Sinico, D Valenti… - International Journal of …, 2024 - Elsevier
Vaccines based on protein antigens have numerous advantages over inactivated
pathogens, including easier manufacturing and improved safety. However, purified antigens …

Nanovaccines: Merits, and diverse roles in boosting antitumor immune responses

Q Yin, Y Wang, Y Xiang, F Xu - Human Vaccines & …, 2022 - Taylor & Francis
An attractive type of cancer immunotherapy is cancer therapeutic vaccines that induce
antitumor immunity effectively. Although supportive results in the recent vaccine studies …