Sperm cryopreservation: A review on current molecular cryobiology and advanced approaches

M Hezavehei, M Sharafi, HM Kouchesfahani… - Reproductive …, 2018 - Elsevier
The cryopreservation of spermatozoa was introduced in the 1960s as a route to fertility
preservation. Despite the extensive progress that has been made in this field, the biological …

Molecular changes induced by oxidative stress that impair human sperm motility

K Nowicka-Bauer, B Nixon - Antioxidants, 2020 - mdpi.com
A state of oxidative stress (OS) and the presence of reactive oxygen species (ROS) in the
male reproductive tract are strongly correlated with infertility. While physiological levels of …

Melatonin inhibits oxidative stress and apoptosis in cryopreserved ovarian tissues via Nrf2/HO-1 signaling pathway

TC Sun, XC Liu, SH Yang, LL Song, SJ Zhou… - Frontiers in Molecular …, 2020 - frontiersin.org
In the field of assisted reproductive technology, female fertility preservation, particularly
ovarian tissue cryopreservation in adolescent cancer patients, has attracted much attention …

Sperm cryopreservation today: Approaches, efficiency, and pitfalls

S Ozimic, H Ban-Frangez, M Stimpfel - Current Issues in Molecular …, 2023 - mdpi.com
The cryopreservation of human spermatozoa has been an option for patients undergoing
chemo or radiotherapies since the late 1950s. Presently, there are different techniques for …

Coping with oxidative stress in reproductive pathophysiology and assisted reproduction: Melatonin as an emerging therapeutical tool

P Cosme, AB Rodríguez, M Garrido, J Espino - Antioxidants, 2022 - mdpi.com
Infertility is an increasing global public health concern with socio-psychological implications
for affected couples. Remarkable advances in reproductive medicine have led to successful …

Melatonin improves the effect of cryopreservation on human oocytes by suppressing oxidative stress and maintaining the permeability of the oolemma

Z Zhang, Y Mu, D Ding, W Zou, X Li… - Journal of Pineal …, 2021 - Wiley Online Library
Cryopreservation causes cryoinjury to oocytes and impairs their developmental
competence. Melatonin (MLT) can improve the effect of cryopreservation in animal oocytes …

Melatonin reduces oxidative damage and upregulates heat shock protein 90 expression in cryopreserved human semen

SL Deng, TC Sun, K Yu, ZP Wang, BL Zhang… - Free Radical Biology …, 2017 - Elsevier
Sperm cells can be damaged during the semen cryopreservation process, decreasing their
fertilizing ability. Physical damage and oxidative stress may occur during the freeze–thawing …

Protective effects of curcumin on the outcome of cryopreservation in human sperm

M Santonastaso, F Mottola, C Iovine, N Colacurci… - Reproductive …, 2021 - Springer
Cryopreservation causes decreased sperm fertility potential due to reactive oxygen species
(ROS) production and physical-chemical damage, resulting in reduced sperm viability and …

Sublethal sperm freezing damage: Manifestations and solutions

T Pini, T Leahy, SP de Graaf - Theriogenology, 2018 - Elsevier
Semen cryopreservation is an important tool for artificial breeding, species conservation and
human reproductive medicine. However, sublethal freezing damage remains an important …

Protective effects of melatonin on male fertility preservation and reproductive system

TC Sun, HY Li, XY Li, K Yu, SL Deng, L Tian - Cryobiology, 2020 - Elsevier
Melatonin is a ubiquitous indoleamine hormone synthesized primarily by the pineal gland.
Diverse biological actions of melatonin involve quite complex mechanisms via its membrane …