Copper complexes as artificial DNA metallonucleases: from Sigman's reagent to next generation anti-cancer agent?
TJP McGivern, S Afsharpour, CJ Marmion - Inorganica Chimica Acta, 2018 - Elsevier
Platinum drugs continue to dominate medical oncology treatments but they have
shortcomings associated with their use including dose-limiting toxic side effects and …
shortcomings associated with their use including dose-limiting toxic side effects and …
An overview on the recent developments of 1, 2, 4-triazine derivatives as anticancer compounds
S Cascioferro, B Parrino, V Spano, A Carbone… - European Journal of …, 2017 - Elsevier
The synthesis, the antitumor activity, the SAR and, whenever described, the possible mode
of action of 1, 2, 4-triazine derivatives, their N-oxides, N, N′-dioxides as well as the benzo …
of action of 1, 2, 4-triazine derivatives, their N-oxides, N, N′-dioxides as well as the benzo …
Synthesis, characterization, crystal structure, DNA and HSA Interactions, and anticancer activity of a mononuclear Cu (II) complex with a Schiff base ligand containing …
A mononuclear Cu (II) complex [Cu (HL)(o-phen)]· H2O (1)[H3L=, o-phen= 1, 10-
phenanthroline] was isolated from methanol, and its X-ray single-crystal structure was …
phenanthroline] was isolated from methanol, and its X-ray single-crystal structure was …
Computational and experimental examinations of new antitumor palladium(II) complex: CT-DNA-/BSA-binding, in-silico prediction, DFT perspective, docking …
AS Dorafshan Tabatabai, E Dehghanian… - Journal of …, 2024 - Taylor & Francis
Since the design of metal complexes with better biological activities is important, herein a
new palladium (II) complex bearing en and acac (en and acac stand for ethylenediamine …
new palladium (II) complex bearing en and acac (en and acac stand for ethylenediamine …
Copper complexes based on chiral Schiff-base ligands: DNA/BSA binding ability, DNA cleavage activity, cytotoxicity and mechanism of apoptosis
Four copper (II) complexes with chiral Schiff-base ligands,[Cu (RL 1) 2]· EtOAc (1) and [Cu
(SL 1) 2]· EtOAc (2),[Cu (RL 2) 2]· EtOAc (3) and [Cu (SL 2) 2]· EtOAc (4),(R/S-HL 1=(R/S)-(1 …
(SL 1) 2]· EtOAc (2),[Cu (RL 2) 2]· EtOAc (3) and [Cu (SL 2) 2]· EtOAc (4),(R/S-HL 1=(R/S)-(1 …
Synthesis of 5‐Trifluoromethyl‐1,4‐dihydro‐1,2,4‐triazines via Base‐mediated [3+3] Cycloaddition of Nitrile Imines and CF3‐Imidoyl Sulfoxonium Ylides
Y Sun, S Ling, Y Duan, J Li, Z Chen… - Advanced Synthesis & …, 2023 - Wiley Online Library
An approach for the construction of 5‐trifluoromethyl‐1, 4‐dihydro‐1, 2, 4‐triazines has been
developed via base‐mediated [3+ 3] cycloaddition of in‐situ generated nitrile imines and …
developed via base‐mediated [3+ 3] cycloaddition of in‐situ generated nitrile imines and …
Binuclear Schiff base copper (II) complexes: Syntheses, crystal structures, HSA interaction and anti-cancer properties
S Jiang, H Ni, F Liu, S Gu, P Yu, Y Gou - Inorganica Chimica Acta, 2020 - Elsevier
Three binuclear Schiff base copper (II) complexes:[Cu 2 (HL1) 2 (CH 3 OH)(NO 3)]· NO 3
(1),[Cu 2 (HL2) 2 (CH 3 OH) 2]· 2NO 3 (2), and [Cu 2 (HL3) 2 (C 2 H 5 OH) 2]· 2NO 3 …
(1),[Cu 2 (HL2) 2 (CH 3 OH) 2]· 2NO 3 (2), and [Cu 2 (HL3) 2 (C 2 H 5 OH) 2]· 2NO 3 …
In vitro Analytical Techniques as Screening Tools to investigate the Metal chelate‐DNA interactions
N Varghese, JR Jose, PM Krishna, D Philip… - …, 2023 - Wiley Online Library
Deoxyribose nucleic acid (DNA) is found to be the most efficient pharmacological target of
many synthetic molecules which are deemed as potential drugs with clinical applications …
many synthetic molecules which are deemed as potential drugs with clinical applications …
A water-soluble Pd (II) complex with a terpyridine ligand: experimental and molecular modeling studies of the interaction with DNA and BSA; and in vitro cytotoxicity …
F Darabi, H Hadadzadeh, J Simpson… - New Journal of …, 2016 - pubs.rsc.org
A new Pd (II) complex,[Pd (4-OHPh-tpy) Cl] Cl, with a ligand that is a terpyridine
derivative,(4′-(4-hydroxyphenyl)-2, 2′, 6′, 2′′-terpyridine (4-OHPh-tpy)), was …
derivative,(4′-(4-hydroxyphenyl)-2, 2′, 6′, 2′′-terpyridine (4-OHPh-tpy)), was …
A mononuclear diketone-based oxido-vanadium (IV) complex: structure, DNA and BSA binding, molecular docking and anticancer activities against MCF-7, HPG-2 …
A mononuclear oxido-vanadium (IV) complex,[VO (L) 2], has been prepared from the
reaction of dibenzoylmethane (HL) and VO (acac) 2 in a 2: 1 molar ratio, and fully …
reaction of dibenzoylmethane (HL) and VO (acac) 2 in a 2: 1 molar ratio, and fully …