Thrombosis as an intravascular effector of innate immunity

B Engelmann, S Massberg - Nature Reviews Immunology, 2013 - nature.com
Thrombosis is the most frequent cause of mortality worldwide and is closely linked to
haemostasis, which is the biological mechanism that stops bleeding after the injury of blood …

Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives

JJ Chiu, S Chien - Physiological reviews, 2011 - journals.physiology.org
Vascular endothelial cells (ECs) are exposed to hemodynamic forces, which modulate EC
functions and vascular biology/pathobiology in health and disease. The flow patterns and …

Hantavirus‐induced immunity in rodent reservoirs and humans

G Schönrich, A Rang, N Lütteke… - Immunological …, 2008 - Wiley Online Library
Hantaviruses are predominantly rodent‐borne pathogens, although recently novel shrew‐
associated hantaviruses were found. Within natural reservoir hosts, hantairuses do not …

Plasmodium falciparum–infected erythrocytes induce NF-κB regulated inflammatory pathways in human cerebral endothelium

AK Tripathi, W Sha, V Shulaev, MF Stins… - Blood, The Journal …, 2009 - ashpublications.org
Cerebral malaria is a severe multifactorial condition associated with the interaction of high
numbers of infected erythrocytes to human brain endothelium without invasion into the brain …

Invasion of Porcine Brain Microvascular Endothelial Cells by Streptococcus suis Serotype 2

G Vanier, M Segura, P Friedl, S Lacouture… - Infection and …, 2004 - Am Soc Microbiol
Streptococcus suis is an important swine pathogen that mainly causes meningitis and
occasionally causes other infections, such as endocarditis, arthritis, and pneumonia. The …

Multiple virulence factors are required for Staphylococcus aureus‐induced apoptosis in endothelial cells

B Haslinger‐Löffler, BC Kahl, M Grundmeier… - Cellular …, 2005 - Wiley Online Library
Staphylococcus aureus infections can result in sepsis and septic shock associated with
vascular damage and multiple organ failure. Apoptosis appears to play a key role during …

Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells

PD N'Guessan, F Riediger, K Vardarova… - … , and vascular biology, 2009 - Am Heart Assoc
Objective—Activation of the endothelium by oxidized low-density lipoprotein (oxLDL) has
been implicated in the development of atherosclerosis. Histone modifications impact on the …

Adrenomedullin and endothelial barrier function

B Temmesfeld-Wollbrueck, AC Hocke… - Thrombosis and …, 2007 - thieme-connect.com
Although loss of endothelial barrier function is a hallmark of every acute inflammation and
contributes to fatal loss of organ function during severe infections, there is no sufficient …

Differential cytotoxic actions of Shiga toxin 1 and Shiga toxin 2 on microvascular and macrovascular endothelial cells

A Bauwens, M Bielaszewska, B Kemper… - Thrombosis and …, 2011 - thieme-connect.com
Shiga toxin (Stx)-mediated injury to vascular endothelial cells in the kidneys, brain and other
organs underlies the pathogenesis of haemolytic uraemic syndrome (HUS) caused by …

Toll‐like receptors signaling network in pre‐eclampsia: An updated review

A Afkham, S Eghbal‐Fard, H Heydarlou… - Journal of cellular …, 2019 - Wiley Online Library
Toll‐like receptors (TLRs) are innate immune cells receptors. They are expressed on
leukocytes, epithelial cells, and more particularly on placental immune cells and chorion …