Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments

SN Lone, S Nisar, T Masoodi, M Singh, A Rizwan… - Molecular cancer, 2022 - Springer
Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly
being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have …

Liquid biopsy enters the clinic—implementation issues and future challenges

M Ignatiadis, GW Sledge, SS Jeffrey - Nature reviews Clinical oncology, 2021 - nature.com
Historically, studies of disseminated tumour cells in bone marrow and circulating tumour
cells in peripheral blood have provided crucial insights into cancer biology and the …

[HTML][HTML] ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group

J Pascual, G Attard, FC Bidard, G Curigliano… - Annals of …, 2022 - Elsevier
Circulating tumour DNA (ctDNA) assays conducted on plasma are rapidly developing a
strong evidence base for use in patients with cancer. The European Society for Medical …

Biomarkers for adjuvant endocrine and chemotherapy in early-stage breast cancer: ASCO guideline update

F Andre, N Ismaila, KH Allison, WE Barlow… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE To update recommendations on appropriate use of breast cancer biomarker
assay results to guide adjuvant endocrine and chemotherapy decisions in early-stage breast …

Detecting liquid remnants of solid tumors: circulating tumor DNA minimal residual disease

EJ Moding, BY Nabet, AA Alizadeh, M Diehn - Cancer discovery, 2021 - AACR
Growing evidence demonstrates that circulating tumor DNA (ctDNA) minimal residual
disease (MRD) following treatment for solid tumors predicts relapse. These results suggest …

Clinical application and detection techniques of liquid biopsy in gastric cancer

S Ma, M Zhou, Y Xu, X Gu, M Zou, G Abudushalamu… - Molecular Cancer, 2023 - Springer
Gastric cancer (GC) is one of the most common tumors worldwide and the leading cause of
tumor-related mortality. Endoscopy and serological tumor marker testing are currently the …

Liquid biopsy and minimal residual disease—latest advances and implications for cure

K Pantel, C Alix-Panabières - Nature Reviews Clinical Oncology, 2019 - nature.com
Liquid biopsy has been introduced as a new diagnostic concept predicated on the analysis
of circulating tumour cells (CTCs) or circulating tumour-derived factors, in particular, cell-free …

Current and future perspectives of liquid biopsies in genomics-driven oncology

E Heitzer, IS Haque, CES Roberts… - Nature Reviews …, 2019 - nature.com
Precision oncology seeks to leverage molecular information about cancer to improve patient
outcomes. Tissue biopsy samples are widely used to characterize tumours but are limited by …

Practical classification of triple-negative breast cancer: intratumoral heterogeneity, mechanisms of drug resistance, and novel therapies

A Marra, D Trapani, G Viale, C Criscitiello… - NPJ breast …, 2020 - nature.com
Triple-negative breast cancer (TNBC) is not a unique disease, encompassing multiple
entities with marked histopathological, transcriptomic and genomic heterogeneity. Despite …

Monitoring and adapting cancer treatment using circulating tumor DNA kinetics: Current research, opportunities, and challenges

E Sanz-Garcia, E Zhao, SV Bratman, LL Siu - Science Advances, 2022 - science.org
Circulating tumor DNA (ctDNA) has emerged as a biomarker with wide-ranging applications
in cancer management. While its role in guiding precision medicine in certain tumors via …