A common hallmark of age‐dependent neurodegenerative diseases is an impairment of
adult neurogenesis. Wingless‐type mouse mammary tumor virus integration site (Wnt)/β …

Since its debut in the biomedical research fields in 1981, zebrafish have been used as a
vertebrate model organism in more than 40,000 biomedical research studies. Especially …

Maintenance of the endothelial blood-brain-barrier (BBB) through Wnt/β-catenin signalling is
essential for neuronal function. The cells however, providing Wnt growth factors at the adult …

The mechanical properties of biological tissues are increasingly recognized as important
factors in developmental and pathological processes. Most existing mechanical …

The inhibitory extracellular matrix in a spinal lesion site is a major impediment to axonal
regeneration in mammals. In contrast, the extracellular matrix in zebrafish allows substantial …

Neural stem/progenitor cells (NSCs) maintain the ability of self-renewal and differentiation
and compose the complex nervous system. Wnt signaling is thought to control the balance of …

Spinal cord injury (SCI) represents one of the most complicated and heterogeneous
pathological processes of central nervous system (CNS) impairments, which is still beyond …

Wingless-type mouse mammary tumor virus (MMTV) integration site (Wnt) signaling is one of
the most critical pathways in developing and adult tissues. In the brain, Wnt signaling …

Central nervous system injury re-initiates neurogenesis in anamniotes (amphibians and
fishes), but not in mammals. Activation of the innate immune system promotes regenerative …

Tissue or organ regeneration is a complex process with successful outcomes depending on
the type of tissue and organism. Upon damage, mammals can only efficiently restore a few …