miRNAs in cancer (review of literature)
B Smolarz, A Durczyński, H Romanowicz… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are short, noncoding, single-stranded RNA molecules that regulate
gene expression at the post-transcriptional level by binding to mRNAs. miRNAs affect the …
gene expression at the post-transcriptional level by binding to mRNAs. miRNAs affect the …
New methods in the diagnosis of cancer and gene therapy of cancer based on nanoparticles
MA Zaimy, N Saffarzadeh, A Mohammadi… - Cancer Gene …, 2017 - nature.com
Cancer is one of the leading cause of death in the world with the prevalence of> 10 million
mortalities annually. Current cancer treatments include surgical intervention, radiation, and …
mortalities annually. Current cancer treatments include surgical intervention, radiation, and …
Regulation and function of miRNA-21 in health and disease
R Kumarswamy, I Volkmann, T Thum - RNA biology, 2011 - Taylor & Francis
The small regulatory RNA microRNA-21 (miR-21) plays a crucial role in a plethora of
biological functions and diseases including development, cancer, cardiovascular diseases …
biological functions and diseases including development, cancer, cardiovascular diseases …
MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells
Q Ji, X Hao, M Zhang, W Tang, M Yang, L Li, D Xiang… - PloS one, 2009 - journals.plos.org
Background MicroRNAs (miRNAs) have been implicated in cancer initiation and
progression via their ability to affect expression of genes and proteins that regulate cell …
progression via their ability to affect expression of genes and proteins that regulate cell …
The fusion of two worlds: Non-coding RNAs and extracellular vesicles-diagnostic and therapeutic implications
Y Sato-Kuwabara, SA Melo… - … journal of oncology, 2015 - spandidos-publications.com
The role of the extracellular non-coding RNAs, particularly microRNAs present in tumor-
derived extravesicles, has been intensively exploited in human cancer as a promising tool …
derived extravesicles, has been intensively exploited in human cancer as a promising tool …
Dysregulation of microRNAs in autoimmune diseases: Pathogenesis, biomarkers and potential therapeutic targets
H Long, X Wang, Y Chen, L Wang, M Zhao, Q Lu - Cancer letters, 2018 - Elsevier
MicroRNAs (miRNAs) are small, single-stranded, endogenous non-coding RNAs that
repress the expression of target genes via post-transcriptional mechanisms. Due to their …
repress the expression of target genes via post-transcriptional mechanisms. Due to their …
DNA polymerases and human disease
LA Loeb, RJ Monnat Jr - Nature Reviews Genetics, 2008 - nature.com
The human genome encodes at least 14 DNA-dependent DNA polymerases—a surprisingly
large number. These include the more abundant, high-fidelity enzymes that replicate the …
large number. These include the more abundant, high-fidelity enzymes that replicate the …
MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents
DR Cochrane, NS Spoelstra, EN Howe… - Molecular cancer …, 2009 - AACR
The transcription factor ZEB1 is normally not expressed in epithelial cells. When
inappropriately expressed in carcinomas, ZEB1 initiates epithelial to mesenchymal transition …
inappropriately expressed in carcinomas, ZEB1 initiates epithelial to mesenchymal transition …
Antagomir-17-5p Abolishes the Growth of Therapy-Resistant Neuroblastoma through p21 and BIM
We identified a key oncogenic pathway underlying neuroblastoma progression: specifically,
MYCN, expressed at elevated level, transactivates the miRNA 17-5p-92 cluster, which …
MYCN, expressed at elevated level, transactivates the miRNA 17-5p-92 cluster, which …
MicroRNAs-Biology and clinical applications
K Ranganathan, V Sivasankar - Journal of Oral and Maxillofacial …, 2014 - journals.lww.com
MicroRNAs are a highly conserved group of small, non-coding RNA molecules, which are
19-25 nucleotides in size. Previously thought to be evolutionary debris with no evident …
19-25 nucleotides in size. Previously thought to be evolutionary debris with no evident …