From flesh to bones: Multi‐omics approaches in forensic science

N Procopio, A Bonicelli - Proteomics, 2024 - Wiley Online Library
Recent advancements in omics techniques have revolutionised the study of biological
systems, enabling the generation of high‐throughput biomolecular data. These innovations …

A set of common buccal CpGs that predict epigenetic age and associate with lifespan-regulating genes

AA Johnson, NS Torosin, MN Shokhirev, TL Cuellar - Iscience, 2022 - cell.com
Epigenetic aging clocks are computational models that use DNA methylation sites to predict
age. Since cheek swabs are non-invasive and painless, collecting DNA from buccal tissue is …

Analyzing the multidimensionality of biological aging with the tools of deep learning across diverse image-based and physiological indicators yields robust age …

A Le Goallec, S Collin, S Diai, JB Prost, MH Jabri… - medRxiv, 2021 - medrxiv.org
It is hypothesized that there are inter-individual differences in biological aging; however,
differences in aging among (heart images vs. electrophysiology) and across (eg, brain vs …

Epigenetics of mitochondria-associated genes in striated muscle

KC Ehrlich, HW Deng, M Ehrlich - Epigenomes, 2021 - mdpi.com
Striated muscle has especially large energy demands. We identified 97 genes preferentially
expressed in skeletal muscle and heart, but not in aorta, and found significant enrichment for …