Membranes surrounding the biological cell and its internal compartments host proteins that
catalyze chemical reactions essential for the functioning of the cell. Rather than being a …

Many years of studies have established that lipids can impact membrane protein structure
and function through bulk membrane effects, by direct but transient annular interactions with …

The interplay between membrane proteins and the lipids of the membrane is important for
cellular function, however, tools enabling the interrogation of protein dynamics within native …

Correctly folded membrane proteins underlie a plethora of cellular processes, but little is
known about how they fold. Knowledge of folding mechanisms centres on reversible folding …

Antimicrobial resistance continues to be a major threat to world health, with the continued
emergence of resistant bacterial strains. Antimicrobial peptides have emerged as an …

The cleavage of protein inside cell membranes regulates pathological pathways and is a
subject of major interest. Thus, the nature of the coupling between the physical environment …

Rhodococcus pyridinivorans B403 is a promising bacterium for degrading phenolic
pollutants. In the application, the high-concentration substrate has a significant inhibitory …

Highlights•Membranes contain distinct traits that shape the evolution of membrane
enzymes.•Results so far suggest that membrane enzyme reaction chemistries are largely …

Protein engineering, the process by which novel proteins with desired properties are
developed, has grown by leaps and bounds since the first examples of protein mutagenesis …

The cockroach allergen Bla g 1 forms a novel fold consisting of 12 amphipathic alpha-
helices enclosing an exceptionally large hydrophobic cavity which was previously …