Members of the Pseudomonas genus produce diverse secondary metabolites affecting other
bacteria, fungi or predating nematodes and protozoa but are also equipped with the capacity …

Bacteria can be genetically engineered to kill specific pathogens or inhibit their virulence.
We previously developed a synthetic genetic system that allows a laboratory strain of …

Bacteria produce a diverse array of antagonistic compounds to restrict growth of microbial
rivals. Contributing to this warfare are bacteriocins: secreted antibacterial peptides, proteins …

Rampant rise of multidrug resistant strains among Gram-negative bacteria has necessitated
investigation of alternative antimicrobial agents with novel modes of action including …

Pyocins are bacteriocins secreted by Pseudomonas aeruginosa, and they assist in the
colonization of different niches. A major subset of these antibacterial proteins adopt a …

Modular bacteriocins represent a major group of secreted protein toxins with a narrow
spectrum of activity, involved in interference competition between Gram-negative bacteria …

Pseudomonas aeruginosa can cause several life-threatening infections among
immunocompromised patients (eg, cystic fibrosis) due to its ability to adapt and develop …

The intestinal carriage rates of Pseudomonas aeruginosa are notably elevated in
immunosuppressed individuals and hospitalized patients, increasing the risk of infection and …

Background Biologically produced alkanes can be used as 'drop in'to existing transportation
infrastructure as alkanes are important components of gasoline and jet fuels. Despite the …

Regulatory mechanisms that direct the synthesis and release of pyocin S5, a surface-acting
bacteriocin produced by Pseudomonas aeruginosa, are relatively unknown. This study aims …