Genomic DNA in the eukaryotic nucleus is hierarchically packaged by histones into
chromatin to fit inside the nucleus. The dynamics of higher-order chromatin compaction play …

Chemotherapy is one of the main therapeutic modalities for cancer patients. Cisplatin
(CDDP), as one of the first-line drugs, is of great importance in the chemotherapy of various …

Through epigenetic modifications, specific long-term phenotypic consequences can arise
from environmental influence on slowly evolving genomic DNA. Heritable epigenetic …

Ovarian cancer is the most common type of gynecologic cancer. One of the leading causes
of high mortality is chemoresistance, developed primarily or during treatment. Different …

Evidence supporting an early origin of prostate cancer is growing. We demonstrated
previously that brief exposure of neonatal rats to estradiol or bisphenol A elevated their risk …

Interconnected functional strategies govern chromatin dynamics in eukaryotic cells. In this
context, A and B type lamins, the nuclear intermediate filaments, act on diverse platforms …

It has been almost a decade since the last review appeared comparing and contrasting the
influences that the different families of High Mobility Group proteins (HMGA, HMGB and …

Purpose The present study is to discover a new genes associated with drug resistance
development in ovarian cancer. Methods We used microarray analysis to determine …

In eukaryotes, genomic DNA is packaged into chromatin in the nucleus. The accessibility of
DNA is dependent on the chromatin structure and dynamics, which essentially control DNA …

MicroRNAs (miRNAs) are a class of small non-coding RNAs which regulate gene
expression at post-transcriptional level. Alterations of miR-186 expression were …