Reassessing the role of milrinone in the treatment of heart failure and pulmonary hypertension in neonates and children: a systematic review and meta-analysis

FY Matsushita, VLJ Krebs, CV de Campos… - European Journal of …, 2024 - Springer
To evaluate milrinone's impact on pediatric cardiac function, focusing on its specific role as
an inotrope and lusitrope, while considering its systemic and pulmonary vasodilatory effects …

Levosimendan in paediatric cardiac anaesthesiology: A systematic review and meta-analysis

M Lapere, F Rega, S Rex - European Journal of Anaesthesiology …, 2022 - journals.lww.com
BACKGROUND Low cardiac output syndrome (LCOS) after congenital cardiac surgery has
an incidence of up to 25%. Preventing and treating LCOS is of pivotal importance as LCOS …

Levosimendan or milrinone for ventricular septal defect repair with pulmonary arterial hypertension

P Nag, SR Chowdhury, SK Behera, M Das… - … of Cardiothoracic and …, 2023 - Elsevier
Objective Both milrinone and levosimendan have been used in patients undergoing surgical
closure of ventricular septal defects (VSD) with pulmonary artery hypertension (PAH); …

Safety of levosimendan in pediatric patients: an up-to-date systematic review

E Pilia, S Silvetti, SM Bohane, E Pusceddu… - … of Cardiothoracic and …, 2024 - Elsevier
Background The potential risks associated with the use of levosimendan in the pediatric
population has not been systematically evaluated. This study aimed to review the available …

Prophylactic use of levosimendan in preoperative setting for surgical repair of congenital heart disease in children

L Wannaz, L Boillat, MH Perez, S Di Bernardo - Frontiers in Pediatrics, 2023 - frontiersin.org
Introduction Low cardiac output syndrome (LCOS) is a significant cause of morbidity and the
leading cause of mortality after pediatric cardiac surgery. Levosimendan has been shown …

An Update on Pharmacologic Management of Neonatal Hypotension: When, Why, and Which Medication

E Agakidou, I Chatziioannidis, A Kontou… - Children, 2024 - mdpi.com
Anti-hypotensive treatment, which includes dopamine, dobutamine, epinephrine,
norepinephrine, milrinone, vasopressin, terlipressin, levosimendan, and glucocorticoids, is a …

Milrinone for the treatment of heart failure caused by severe Pneumonia in children with congenital heart disease: a meta-analysis

W Shao, S Diao, L Zhou, L Cai - BMC pediatrics, 2023 - Springer
Background Children with congenital heart disease (CHD) are easily complicated by severe
pneumonia and heart failure. We aimed to conduct a meta-analysis to evaluate the effects …

Comparison of Levosimendan Versus Milrinone After the Arterial Switch Operation for Infants≤ 3 kg

RK Joshi, R Joshi, N Aggarwal… - World Journal for …, 2024 - journals.sagepub.com
Background: Various inotropes and inodilators have been utilized to treat low cardiac output
syndrome after the arterial switch operation. The use of levosimendan, a calcium sensitizer …

[HTML][HTML] Современные и потенциальные возможности применения левосимендана в лечении сердечной недостаточности и септического шока: обзор …

ВА Бобошко, ЕИ Зибарева… - … терапии имени АИ …, 2023 - cyberleninka.ru
Левосимендан относят к классу препаратов-сенситизаторов кальция, который
проявляет свои положительные инотропные эффекты за счет увеличения сродства …

Efficacy and Safety of Milrinone in Treating Heart Failure Induced by Severe Pneumonia in Children with Congenital Heart Disease: A Systematic Review

ARTTA Ribka, T Tarigan… - … of Pediatric and …, 2024 - medicaljournalinternational.org
Background: Congenital heart disease (CHD) is a prevalent pediatric heart condition, often
complicated by severe pneumonia. Milrinone, a second-generation phosphodiesterase …