Multimodal brain and retinal imaging of dopaminergic degeneration in Parkinson disease
JY Lee, A Martin-Bastida, A Murueta-Goyena… - Nature Reviews …, 2022 - nature.com
Parkinson disease (PD) is a progressive disorder characterized by dopaminergic
neurodegeneration in the brain. The development of parkinsonism is preceded by a long …
neurodegeneration in the brain. The development of parkinsonism is preceded by a long …
Parkinson disease
W Poewe, K Seppi, CM Tanner, GM Halliday… - Nature reviews Disease …, 2017 - nature.com
Parkinson disease is the second-most common neurodegenerative disorder that affects 2–
3% of the population≥ 65 years of age. Neuronal loss in the substantia nigra, which causes …
3% of the population≥ 65 years of age. Neuronal loss in the substantia nigra, which causes …
[HTML][HTML] Neuromelanin detection by magnetic resonance imaging (MRI) and its promise as a biomarker for Parkinson's disease
The diagnosis of Parkinson's disease (PD) occurs after pathogenesis is advanced and many
substantia nigra (SN) dopamine neurons have already died. Now that therapies to block this …
substantia nigra (SN) dopamine neurons have already died. Now that therapies to block this …
Imaging the substantia nigra in Parkinson disease and other Parkinsonian syndromes
Parkinson disease is characterized by dopaminergic cell loss in the substantia nigra of the
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …
[HTML][HTML] Magnetic resonance imaging for the diagnosis of Parkinson's disease
B Heim, F Krismer, R De Marzi, K Seppi - Journal of neural transmission, 2017 - Springer
The differential diagnosis of parkinsonian syndromes is considered one of the most
challenging in neurology and error rates in the clinical diagnosis can be high even at …
challenging in neurology and error rates in the clinical diagnosis can be high even at …
[HTML][HTML] The concept of prodromal Parkinson's disease
P Mahlknecht, K Seppi… - Journal of Parkinson's …, 2015 - content.iospress.com
Parkinson's disease (PD) is currently clinically defined by a set of cardinal motor features
centred on the presence of bradykinesia and at least one additional motor symptom out of …
centred on the presence of bradykinesia and at least one additional motor symptom out of …
[HTML][HTML] Neuromelanin imaging and dopaminergic loss in Parkinson's disease
Parkinson's disease (PD) is a progressive neurodegenerative disorder in which the major
pathologic substrate is a loss of dopaminergic neurons from the substantia nigra. Our main …
pathologic substrate is a loss of dopaminergic neurons from the substantia nigra. Our main …
Meta‐analysis of dorsolateral nigral hyperintensity on magnetic resonance imaging as a marker for Parkinson's disease
Background Dorsolateral nigral hyperintensity on iron‐sensitive magnetic resonance
imaging (MRI) sequences seems to be a typical finding in Parkinson's disease (PD), but …
imaging (MRI) sequences seems to be a typical finding in Parkinson's disease (PD), but …
[HTML][HTML] Imaging the Nigrosome 1 in the substantia nigra using susceptibility weighted imaging and quantitative susceptibility mapping: An application to Parkinson's …
Parkinson's disease (PD) is a clinically heterogeneous chronic progressive neuro-
degenerative disease with loss of dopaminergic neurons in the nigrosome 1 (N1) territory of …
degenerative disease with loss of dopaminergic neurons in the nigrosome 1 (N1) territory of …
[HTML][HTML] Neuroimaging at 7 Tesla: a pictorial narrative review
T Okada, K Fujimoto, Y Fushimi, T Akasaka… - … imaging in medicine …, 2022 - ncbi.nlm.nih.gov
Abstract Neuroimaging using the 7-Tesla (7T) human magnetic resonance (MR) system is
rapidly gaining popularity after being approved for clinical use in the European Union and …
rapidly gaining popularity after being approved for clinical use in the European Union and …