Human listeriosis

MM Koopmans, MC Brouwer… - Clinical Microbiology …, 2023 - Am Soc Microbiol
Listeria monocytogenes is a Gram-positive facultative intracellular pathogen that can cause
severe invasive infections upon ingestion with contaminated food. Clinically, listerial …

Listeria monocytogenes: cell biology of invasion and intracellular growth

J Pizarro-Cerda, P Cossart - Microbiology spectrum, 2018 - Am Soc Microbiol
ABSTRACT The Gram-positive pathogen Listeria monocytogenes is able to promote its entry
into a diverse range of mammalian host cells by triggering plasma membrane remodeling …

Actin-based motility and cell-to-cell spread of bacterial pathogens

RL Lamason, MD Welch - Current opinion in microbiology, 2017 - Elsevier
Highlights•Intracellular bacterial pathogens use different strategies for actin-based
motility.•Diverse networks of host and bacterial proteins coordinate motility.•Pathogens also …

COPII-dependent ER export in animal cells: adaptation and control for diverse cargo

J McCaughey, DJ Stephens - Histochemistry and cell biology, 2018 - Springer
The export of newly synthesized proteins from the endoplasmic reticulum is fundamental to
the ongoing maintenance of cell and tissue structure and function. After co-translational …

[HTML][HTML] Manipulation of host membranes by the bacterial pathogens Listeria, Francisella, Shigella and Yersinia

J Pizarro-Cerdá, A Charbit, J Enninga, F Lafont… - Seminars in cell & …, 2016 - Elsevier
Bacterial pathogens display an impressive arsenal of molecular mechanisms that allow
survival in diverse host niches. Subversion of plasma membrane and cytoskeletal functions …

Listeria monocytogenes exploits host exocytosis to promote cell-to-cell spread

GC Dowd, R Mortuza, M Bhalla… - Proceedings of the …, 2020 - National Acad Sciences
The facultative intracellular pathogen Listeria monocytogenes uses an actin-based motility
process to spread within human tissues. Filamentous actin from the human cell forms a tail …

The host GTPase Dynamin 2 modulates apical junction structure to control cell-to-cell spread of Listeria monocytogenes

S Tijoriwalla, T Liyanage, TUB Herath, N Lee… - Infection and …, 2024 - journals.asm.org
The food-borne pathogen Listeria monocytogenes uses actin-based motility to generate
plasma membrane protrusions that mediate the spread of bacteria between host cells. In …

Listeria monocytogenes co-opts the host exocyst complex to promote internalin A-mediated entry

GC Gyanwali, TUB Herath, A Gianfelice… - Infection and …, 2022 - Am Soc Microbiol
The bacterial pathogen Listeria monocytogenes induces its internalization (entry) into
intestinal epithelial cells through interaction of its surface protein, internalin A (InlA), with the …

Bacterial spread from cell to cell: beyond actin-based motility

CJ Kuehl, AM Dragoi, A Talman, H Agaisse - Trends in microbiology, 2015 - cell.com
Several intracellular pathogens display the ability to propagate within host tissues by
displaying actin-based motility in the cytosol of infected cells. As motile bacteria reach cell …

A role for host cell exocytosis in InlB‐mediated internalisation of Listeria monocytogenes

H Van Ngo, M Bhalla, DY Chen… - Cellular Microbiology, 2017 - Wiley Online Library
The bacterial surface protein InlB mediates internalisation of Listeria monocytogenes into
human cells through interaction with the host receptor tyrosine kinase, Met. InlB‐mediated …