[HTML][HTML] Plausible biochemical mechanisms of chemotherapy-induced cognitive impairment (“chemobrain”), a condition that significantly impairs the quality of life of …

X Ren, D Boriero, L Chaiswing, S Bondada… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Increasing numbers of cancer patients survive and live longer than five years after therapy,
but very often side effects of cancer treatment arise at same time. One of the side effects …

Chemotherapy and cognition: comprehensive review on doxorubicin-induced chemobrain

SE El-Agamy, AK Abdel-Aziz, A Esmat… - Cancer chemotherapy and …, 2019 - Springer
Chemobrain refers to a common sequela experienced by a substantial subset of cancer
patients exposed to chemotherapeutic treatment, a phenomenon that dramatically …

Chemobrain in breast cancer: mechanisms, clinical manifestations, and potential interventions

GR Onzi, N D'Agustini, SC Garcia, SS Guterres… - Drug safety, 2022 - Springer
Among the potential adverse effects of breast cancer treatment, chemotherapy-related
cognitive impairment (CRCI) has gained increased attention in the past years. In this review …

Chemotherapy-induced cognitive impairments: A systematic review of the animal literature

A Matsos, IN Johnston - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
Whilst chemotherapy is a widely used anti-cancer treatment, a subset of patients experience
cognitive decline. However, cancer type, treatment regimen, fatigue and anxiety can …

The microbiota-gut-brain axis: An emerging therapeutic target in chemotherapy-induced cognitive impairment

CB Subramaniam, JM Bowen, MA Gladman… - Neuroscience & …, 2020 - Elsevier
Chemotherapy-induced cognitive impairment (CICI) is an ill-defined complication of
chemotherapy treatment that places a significant psychosocial burden on survivors of cancer …

Chemobrain in rats: Behavioral, morphological, oxidative and inflammatory effects of doxorubicin administration

CV Cardoso, MP de Barros, ALL Bachi… - Behavioural brain …, 2020 - Elsevier
Doxorubicin (DOX) is known to cause cognitive impairments in patients submitted to long-
term chemotherapy (deficits also known as chemobrain). The present study investigated …

Paclitaxel induces sex-biased behavioral deficits and changes in gene expression in mouse prefrontal cortex

L Liang, J Wei, L Tian, BVP Nagendra, F Gao, J Zhang… - Neuroscience, 2020 - Elsevier
Paclitaxel (PTX) is one of the most commonly used chemotherapeutic agents for various
cancer diseases. Despite its advantages, PTX also causes behavioral deficits related to …

Chemotherapy-induced cognitive impairment: focus on the intersection of oxidative stress and TNFα

NG Rummel, L Chaiswing, S Bondada… - Cellular and Molecular …, 2021 - Springer
Chemotherapy-induced cognitive impairment (CICI) has been observed in a large fraction of
cancer survivors. Although many of the chemotherapeutic drugs do not cross the blood …

Cancer related cognitive impairment: a downside of cancer treatment

K Demos-Davies, J Lawrence, D Seelig - Frontiers in Oncology, 2024 - frontiersin.org
Cancer treatment is associated with long lasting cognitive impairment in cancer survivors.
This cognitive impairment is often termed cancer related cognitive impairment (CRCI) …

Resveratrol Improves Paclitaxel-Induced Cognitive Impairment in Mice by Activating SIRT1/PGC-1α Pathway to Regulate Neuronal State and Microglia Cell …

X Liu, M Tang, TY He, S Zhao, HZ Li, Z Li… - Drug Design …, 2023 - Taylor & Francis
Objective This study aimed to investigate the effect of resveratrol (Res) on paclitaxel (PTX)-
induced cognitive impairment and elucidate the underlying molecular mechanisms. Methods …