The past three decades have borne witness to many advances in the understanding of the
molecular biology and treatment of nasopharyngeal carcinoma (NPC), an Epstein–Barr virus …

This study aims to identify prognostic factors in nasopharyngeal carcinoma (NPC) to improve
the current 8th edition TNM classification. A systematic review of the literature reported …

Summary The AJCC/UICC TNM classification describes anatomic extent of tumor
progression and guides treatment decisions. Our comprehensive analysis of 8,834 newly …

Tumor breaching the capsule of a lymph node is termed extranodal extension (ENE). It
reflects aggressiveness of a tumor, creates anatomic challenges for disease clearance, and …

Currently, the features and prognosis of nasopharyngeal carcinoma (NPC) with distant
metastases are still rarely reported. Thus, the main purpose of our study was to investigate …

Background and purpose To explore the prognostic value of different radiologic extranodal
extension (rENE) grades and their potential improvement for the 8th edition N category in …

Objective The early response to concurrent chemoradiotherapy in patients with locally
advanced nasopharyngeal carcinoma (LA-NPC) is closely correlated with prognosis. In this …

Purpose We evaluated the prognostic value of various grades of radiologic extranodal
extension (rENE) and their potential roles in N-classification refinement for nasopharyngeal …

Purpose To confirm the prognostic value of radiologic extranodal extension (rENE) and its
role in clinical-N classification in nasopharyngeal carcinoma (NPC) treated in a western …

Importance Accurate staging is a fundamental step in treating patients with nasopharyngeal
carcinoma (NPC) worldwide; this is crucial not only for prognostication, but also for guiding …