[HTML][HTML] Amino acids in the regulation of aging and aging-related diseases

CA Canfield, PC Bradshaw - Translational Medicine of Aging, 2019 - Elsevier
Amino acids are the building blocks of protein, but also play important cellular signaling
roles. The mechanisms through which altered levels of many amino acids are sensed and …

The GCN5: its biological functions and therapeutic potentials

ME Haque, M Jakaria, M Akther, DY Cho… - Clinical …, 2021 - portlandpress.com
General control non-depressible 5 (GCN5) or lysine acetyltransferase 2A (KAT2A) is one of
the most highly studied histone acetyltransferases. It acts as both histone acetyltransferase …

[图书][B] Amino acids: biochemistry and nutrition

G Wu - 2021 - taylorfrancis.com
Following its predecessor, the second edition of Amino Acids: Biochemistry and Nutrition
presents exhaustive coverage of amino acids in the nutrition, metabolism and health of …

Acetyltransferase GCN5 regulates autophagy and lysosome biogenesis by targeting TFEB

Y Wang, Y Huang, J Liu, J Zhang, M Xu, Z You… - EMBO …, 2020 - embopress.org
Accumulating evidence highlights the role of histone acetyltransferase GCN5 in the
regulation of cell metabolism in metazoans. Here, we report that GCN5 is a negative …

[HTML][HTML] Rumen-protected choline reduces hepatic lipidosis by increasing hepatic triacylglycerol-rich lipoprotein secretion in dairy cows

U Arshad, A Husnain, MB Poindexter, R Zimpel… - Journal of Dairy …, 2023 - Elsevier
Objectives were to determine the effects of supplementing rumen-protected choline (RPC)
on hepatic composition and secretion of triacylglycerol-rich lipoprotein when cows were …

Methionine as a double-edged sword in health and disease: Current perspective and future challenges

U Navik, VG Sheth, A Khurana, SS Jawalekar… - Ageing research …, 2021 - Elsevier
Methionine is one of the essential amino acids and plays a vital role in various cellular
processes. Reports advocate that methionine restriction and supplementation provide …

GCN5 acetyltransferase in cellular energetic and metabolic processes

B Mutlu, P Puigserver - Biochimica et Biophysica Acta (BBA)-Gene …, 2021 - Elsevier
Abstract General Control Non-repressed 5 protein (GCN5), encoded by the mammalian
gene Kat2a, is the first histone acetyltransferase discovered to link histone acetylation to …

Interactive effects of water salinity and dietary methionine levels on growth performance, whole-body composition, plasma parameters, and expression of major …

H Xu, M Ren, H Liang, X Ge, K Ji, D Huang, H Yu, L Wu - Aquaculture, 2022 - Elsevier
Salinity is an important factor in the water environment, and salinity can cause changes in
fish metabolism, which may be further reflected by changes in feed nutrient requirements …

[HTML][HTML] Rumen-protected methionine during heat stress alters mTOR, insulin signaling, and 1-carbon metabolism protein abundance in liver, and whole-blood …

DN Coleman, P Totakul, N Onjai-Uea, A Aboragah… - Journal of Dairy …, 2022 - Elsevier
We investigated effects of rumen-protected Met (RPM) during a heat stress (HS) challenge
on (1) hepatic abundance of mTOR, insulin, and antioxidant signaling proteins,(2) enzymes …

Metabolic load comparison between the quarters of a game in elite male basketball players using sport metabolomics

K Khoramipour, AA Gaeini, E Shirzad… - European Journal of …, 2021 - Taylor & Francis
Purpose: A basketball match is characterized by intermittent high-intensity activities, thereby
relying extensively on both aerobic and anaerobic metabolic pathways. Here, we aimed to …