Evaluating the role of trypsin in silk degumming: An in silico approach
JP Pandey, DM Pandey - Journal of Biotechnology, 2022 - Elsevier
The trypsin being universal enzyme forming family of proteases catalyzes the hydrolysis of
proteins into amino acids and regenerates the serine hydroxyl an active site. The trypsin …
proteins into amino acids and regenerates the serine hydroxyl an active site. The trypsin …
Designing a fusion protein vaccine against HCV: an in silico approach
A Atapour, P Mokarram, Z MostafaviPour… - International Journal of …, 2019 - Springer
Hepatitis C virus (HCV) infection is a major global issue that leads to serious liver disease
such as chronic liver inflammation and hepatocellular carcinoma. At present, no approved …
such as chronic liver inflammation and hepatocellular carcinoma. At present, no approved …
Effects of synonymous mutations on kinetic properties and structure of firefly luciferase: Molecular dynamics simulation, molecular docking, RNA folding, and …
M Mortazavi, M Torkzadeh-Mahani, M Rahimi… - International Journal of …, 2023 - Elsevier
Although synonymous mutations have long been thought to lack striking results, a growing
body of research shows these mutations have highly variable effects. In this study, the …
body of research shows these mutations have highly variable effects. In this study, the …
[HTML][HTML] Bioinformatic identification of rare codon clusters (RCCs) in HBV genome and evaluation of RCCs in proteins structure of Hepatitis B Virus
M Mortazavi, M Zarenezhad, S Gholamzadeh… - Hepatitis …, 2016 - ncbi.nlm.nih.gov
Background Hepatitis B virus (HBV) as an infectious disease that has nine genotypes (AI)
and a 'putative'genotype J. Objectives The aim of this study was to identify the rare codon …
and a 'putative'genotype J. Objectives The aim of this study was to identify the rare codon …
Surface charge modification increases firefly luciferase rigidity without alteration in bioluminescence spectra
M Mortazavi, S Hosseinkhani - Enzyme and Microbial Technology, 2017 - Elsevier
Protein engineering can provide useful approaches for loop anchoring and mutation of
surface-exposed loop residues to Arg for the design of thermostable proteins. In this context …
surface-exposed loop residues to Arg for the design of thermostable proteins. In this context …
In silico analysis of codon usage and rare codon clusters in the halophilic bacteria L-asparaginase
L-asparagine is essential for the correct function of some neoplastic cells; in lymphoblasts, L-
asparagine is converted to aspartic acid by L-asparaginase. By conversion of L-asparagine …
asparagine is converted to aspartic acid by L-asparaginase. By conversion of L-asparagine …
Isolation, identification and in silico study of native cellulase producing bacteria
Aim: The purpose of this study was to screen the bacteria producing cellulase enzymes and
their bioinformatics studies. Background: Cellulose is a long-chain polymer of glucose that …
their bioinformatics studies. Background: Cellulose is a long-chain polymer of glucose that …
Suicide gene therapy: A special focus on progress and concerns about cancer treatment
A Gholami - Trends in Pharmaceutical Sciences, 2017 - tips.sums.ac.ir
Suicide gene therapy is based on transfer of a suicide viral or a bacterial gene into tumor
cells. Expression of these genes leads to non-toxic substances in cell convert to lethal …
cells. Expression of these genes leads to non-toxic substances in cell convert to lethal …
Evaluation of Luciferase Thermal Stability by Arginine Saturation in the Flexible Loops
Background: The firefly luciferase enzyme is widely used in protein engineering and diverse
areas of biotechnology, but the main problem with this enzyme is low-temperature stability …
areas of biotechnology, but the main problem with this enzyme is low-temperature stability …
In silico Evaluation of Substrate Binding Site and Rare Codons in the Structure of CYP152A1
Background: The Cytochromes P450 (CYPs) have an essential role in the oxidation of
endogenous and exogenous molecules. The CYPs are identified in all domains of life, but …
endogenous and exogenous molecules. The CYPs are identified in all domains of life, but …