The trypsin being universal enzyme forming family of proteases catalyzes the hydrolysis of
proteins into amino acids and regenerates the serine hydroxyl an active site. The trypsin …

Hepatitis C virus (HCV) infection is a major global issue that leads to serious liver disease
such as chronic liver inflammation and hepatocellular carcinoma. At present, no approved …

Although synonymous mutations have long been thought to lack striking results, a growing
body of research shows these mutations have highly variable effects. In this study, the …

Background Hepatitis B virus (HBV) as an infectious disease that has nine genotypes (AI)
and a 'putative'genotype J. Objectives The aim of this study was to identify the rare codon …

Protein engineering can provide useful approaches for loop anchoring and mutation of
surface-exposed loop residues to Arg for the design of thermostable proteins. In this context …

L-asparagine is essential for the correct function of some neoplastic cells; in lymphoblasts, L-
asparagine is converted to aspartic acid by L-asparaginase. By conversion of L-asparagine …

Aim: The purpose of this study was to screen the bacteria producing cellulase enzymes and
their bioinformatics studies. Background: Cellulose is a long-chain polymer of glucose that …

Suicide gene therapy is based on transfer of a suicide viral or a bacterial gene into tumor
cells. Expression of these genes leads to non-toxic substances in cell convert to lethal …

Background: The firefly luciferase enzyme is widely used in protein engineering and diverse
areas of biotechnology, but the main problem with this enzyme is low-temperature stability …

Background: The Cytochromes P450 (CYPs) have an essential role in the oxidation of
endogenous and exogenous molecules. The CYPs are identified in all domains of life, but …