[HTML][HTML] The critical roles of histone deacetylase 3 in the pathogenesis of solid organ injury
L Ning, X Rui, W Bo, G Qing - Cell death & disease, 2021 - nature.com
Abstract Histone deacetylase 3 (HDAC3) plays a crucial role in chromatin remodeling,
which, in turn, regulates gene transcription. Hence, HDAC3 has been implicated in various …
which, in turn, regulates gene transcription. Hence, HDAC3 has been implicated in various …
Differential regulation of the BDNF gene in cortical and hippocampal neurons
EE Esvald, J Tuvikene, A Moistus… - Journal of …, 2022 - Soc Neuroscience
Brain-derived neurotrophic factor (BDNF) is a widely expressed neurotrophin that supports
the survival, differentiation, and signaling of various neuronal populations. Although it has …
the survival, differentiation, and signaling of various neuronal populations. Although it has …
[HTML][HTML] Prox1 Suppresses the Proliferation of Breast Cancer Cells via Direct Inhibition of c-Myc Gene Expression
A Michail, D Gkikas, D Stellas, V Kaltezioti, PK Politis - Cells, 2023 - mdpi.com
Breast cancer is one of the most lethal malignancies in women worldwide and is
characterized by rapid growth and low survival rates, despite advances in tumor biology and …
characterized by rapid growth and low survival rates, despite advances in tumor biology and …
The Neurodevelopmental Disorders Associated Gene Rnf113a Regulates Survival and Differentiation Properties of Neural Stem Cells
M Tsampoula, I Tarampoulous, T Manolakou… - Stem Cells, 2022 - academic.oup.com
Abstract RNF113A (Ring Finger Protein 113A) is genetically associated with autism
spectrum disorders and X-linked trichothiodystrophy (TTD) syndrome. Loss-of-function …
spectrum disorders and X-linked trichothiodystrophy (TTD) syndrome. Loss-of-function …
Knockdown of PROX1 promotes milk fatty acid synthesis by targeting PPARGC1A in dairy goat mammary gland
Q He, W Yao, J Luo, J Wu, F Zhang, C Li, L Gao… - International Journal of …, 2024 - Elsevier
Goat milk is rich in various fatty acids that are beneficial to human health. Chromatin
immunoprecipitation followed by sequencing (ChIP-seq) and RNA-seq analyses of goat …
immunoprecipitation followed by sequencing (ChIP-seq) and RNA-seq analyses of goat …
[HTML][HTML] Cromolyn platform suppresses fibrosis and inflammation, promotes microglial phagocytosis and neurite outgrowth
YJ Wang, MA Downey, S Choi, TM Shoup… - Scientific Reports, 2021 - nature.com
Neurodegenerative diseases are characterized by chronic neuroinflammation and may
perpetuate ongoing fibrotic reactions within the central nervous system. Unfortunately, there …
perpetuate ongoing fibrotic reactions within the central nervous system. Unfortunately, there …
[HTML][HTML] Regulation of otic neurosensory specification by Notch and Wnt signalling: insights from RNA-seq screenings in the embryonic chicken inner ear
The Notch and Wnt signalling pathways play key roles in the formation of inner ear sensory
organs, but little is known about their transcriptional effectors and targets in this context …
organs, but little is known about their transcriptional effectors and targets in this context …
[HTML][HTML] Postmitotic Prox1 expression controls the final specification of cortical VIP interneuron subtypes
TJ Stachniak, R Kastli, O Hanley… - Journal of …, 2021 - Soc Neuroscience
Throughout development, neuronal identity is controlled by key transcription factors that
determine the unique properties of a cell. During embryogenesis, the transcription factor …
determine the unique properties of a cell. During embryogenesis, the transcription factor …
[HTML][HTML] Long Non-Coding RNA Lacuna Regulates Neuronal Differentiation of Neural Stem Cells During Brain Development
E Ninou, A Michail, PK Politis - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Although long non-coding RNAs (lncRNAs) is one of the most abundant classes of RNAs
encoded within the mammalian genome and are highly expressed in the adult brain, they …
encoded within the mammalian genome and are highly expressed in the adult brain, they …
Quantifying adaptive divergence of the snowfinches in a common landscape
H She, Z Jiang, G Song, PGP Ericson… - Diversity and …, 2022 - Wiley Online Library
Aim Species living in a shared environment face similar selective pressures and often
evolve adaptive divergence to avoid competition. Quantifying phenotypic divergence and its …
evolve adaptive divergence to avoid competition. Quantifying phenotypic divergence and its …