Microneedle arrays for drug delivery and diagnostics: toward an optimized design, reliable insertion, and penetration
V Ebrahiminejad, PD Prewett… - Advanced Materials …, 2022 - Wiley Online Library
In the past two decades, microneedles have been extensively studied for transdermal
delivery of drug or vaccines and for bio‐fluid extraction. Microneedle‐based devices consist …
delivery of drug or vaccines and for bio‐fluid extraction. Microneedle‐based devices consist …
[HTML][HTML] Insights into the mechanics of solid conical microneedle array insertion into skin using the finite element method
In order to develop optimum microneedle designs, researchers must first develop robust,
repeatable and adaptable test methods which are representative of in vivo conditions …
repeatable and adaptable test methods which are representative of in vivo conditions …
Forensic veterinary pathology: sharp injuries in animals
A De Siqueira, SEC Cuevas, FA Salvagni… - Veterinary …, 2016 - journals.sagepub.com
Sharp-force injuries are injuries caused by a mechanical force using sharp objects against
the skin. Sharp-force injuries are mainly classified as stab, incised, chop, and therapeutic …
the skin. Sharp-force injuries are mainly classified as stab, incised, chop, and therapeutic …
[图书][B] Simpson's forensic medicine
J Payne-James, RM Jones - 2019 - taylorfrancis.com
Prestigious and authoritative, this fully updated fourteenth edition of Simpson's Forensic
Medicine remains a classic; one of the world's leading introductory texts in the field of …
Medicine remains a classic; one of the world's leading introductory texts in the field of …
The biomechanics of autoinjector-skin interactions during dynamic needle insertion
Autoinjector devices are rapidly becoming the preferred method of drug delivery for a wide
array of pharmaceuticals such as monoclonal antibodies. Yet, our understanding of injection …
array of pharmaceuticals such as monoclonal antibodies. Yet, our understanding of injection …
Honeybee stinger-based biopsy needle and influence of the barbs on needle forces during insertion/extraction into the iliac crest: a multilayer finite element approach
Bone marrow biopsy (BMB) needles are frequently used in medical procedures, including
extracting biological tissue to identify specific lesions or abnormalities discovered during a …
extracting biological tissue to identify specific lesions or abnormalities discovered during a …
Piercing the surface: a mechanical analysis of stabbing with household tools
V Heckmann, V Engum, G Simon… - Journal of forensic …, 2023 - Wiley Online Library
Estimating the applied power during a stabbing incident, or estimating the minimal force
necessary to penetrate the body with a certain weapon is a challenging task in forensic …
necessary to penetrate the body with a certain weapon is a challenging task in forensic …
Assessment of bacterial nanocellulose loaded with acetylsalicylic acid or povidone-iodine as bioactive dressings for skin and soft tissue infections
S Argel, M Castaño, DE Jimenez, S Rodríguez… - Pharmaceutics, 2022 - mdpi.com
Bacterial nanocellulose (BNC) is a novel nanomaterial known for its large surface area,
biocompatibility, and non-toxicity. BNC contributes to regenerative processes in the skin but …
biocompatibility, and non-toxicity. BNC contributes to regenerative processes in the skin but …
The hyperelastic and failure behaviors of skin in relation to the dynamic application of microscopic penetrators in a murine model
In-depth understanding of skin elastic and rupture behavior is fundamental to enable next-
generation biomedical devices to directly access areas rich in cells and biomolecules …
generation biomedical devices to directly access areas rich in cells and biomolecules …
Mechanical damage in porcine dermis: Micro-mechanical model and experimental characterization
Skin is subjected to extreme mechanical loading during needle insertion and drug delivery
to the subcutaneous space. There is a rich literature on the characterization of porcine skin …
to the subcutaneous space. There is a rich literature on the characterization of porcine skin …