The early endosome (EE), also known as the sorting endosome (SE) is a crucial station for
the sorting of cargoes, such as receptors and lipids, through the endocytic pathways. The …

Regulation of endocytic transport is controlled by an elaborate network of proteins. Rab GTP-
binding proteins and their effectors have well-defined roles in mediating specific endocytic …

Eps15 homology domain–containing 2 (EHD2) belongs to the EHD-containing protein family
of dynamin-related ATPases involved in membrane remodeling in the endosomal system …

Significance: The molecules interacting with CasL (MICAL) family members participate in a
multitude of activities, including axonal growth cone repulsion, membrane trafficking …

Endocytic transport necessitates the generation of membrane tubules and their subsequent
fission to transport vesicles for sorting of cargo molecules. The endocytic recycling …

Endocytosis is a conserved process across species in which cell surface receptors and
lipids are internalized from the plasma membrane. Once internalized, receptors can either …

TCF/LEF factors are ancient context-dependent enhancer-binding proteins that are activated
by β-catenin following Wnt signaling. They control embryonic development and adult stem …

Endocytosis is a conserved cellular process in which nutrients, lipids, and receptors are
internalized and transported to early endosomes, where they are sorted and either …

Rabankyrin‐5 (Rank‐5) has been implicated as an effector of the small GTPase Rab 5 and
plays an important role in macropinocytosis. We have now identified Rank‐5 as an …

Members of the four-member C-terminal EPS15-Homology Domain-containing (EHD)
protein family play crucial roles in endocytic recycling of cell surface receptors from …