Aims Deprescribing is a suggested intervention to reverse the potential iatrogenic harms of
inappropriate polypharmacy. The review aimed to determine whether or not deprescribing is …

An estimated 24 million people worldwide have dementia, the majority of whom are thought
to have Alzheimer's disease. Thus, Alzheimer's disease represents a major public health …

The goal of this guideline is to improve the care of patients with dementia who are exhibiting
agitation or psychosis. More specifically, this guideline focuses on the judicious use of …

Background Agitation is a common, challenging symptom affecting large numbers of people
with dementia and impacting on quality of life (QoL). There is an urgent need for evidence …

Neuropsychiatric symptoms (NPS) are core features of Alzheimer's disease and related
dementias. Once thought to emerge primarily in people with late-stage disease, these …

Objective To develop an evidence-based guideline to help clinicians make decisions about
when and how to safely taper and stop antipsychotics; to focus on the highest level of …

Introduction. Behavioral and psychological symptoms of dementia (BPSD) are defined as a
group of symptoms of disturbed perceptive thought content, mood, or behavior that include …

Behavioral symptoms such as repetitive speech, wandering, and sleep disturbances are a
core clinical feature of Alzheimer disease and related dementias. If untreated, these …

Background Treatment-resistant major depression is common and potentially life-
threatening in elderly people, in whom little is known about the benefits and risks of …

Aims. Mortality-associated burden of disease estimates from the Global Burden of Disease
2010 (GBD 2010) may erroneously lead to the interpretation that premature death in people …