Antibacterial activities with the structure-activity relationship of coumarin derivatives

HL Qin, ZW Zhang, L Ravindar, KP Rakesh - European journal of medicinal …, 2020 - Elsevier
The development of drug-resistant bacteria, as well as multidrug-resistant pathogens related
to substantial mortality, is an important global health threat. The wide range of biological …

Pyrazole-based analogs as potential antibacterial agents against methicillin-resistance staphylococcus aureus (MRSA) and its SAR elucidation

R Verma, SK Verma, KP Rakesh, YR Girish… - European journal of …, 2021 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) is becoming lethal to humanity due to
easy transmission and difficult-to-treat skin and flimsy diseases. The most threatening aspect …

Antibacterial activities of sulfonyl or sulfonamide containing heterocyclic derivatives and its structure-activity relationships (SAR) studies: A critical review

SK Verma, R Verma, F Xue, PK Thakur, YR Girish… - Bioorganic …, 2020 - Elsevier
The rise of drug-resistance has made the deserted clinical requirement to improve of new
classes of antibiotics agents. The development of antibacterial agents with the novel method …

Chemical and biology of sulfur fluoride exchange (SuFEx) click chemistry for drug discovery

SW Lucas, RZ Qin, KP Rakesh, KSS Kumar, HL Qin - Bioorganic Chemistry, 2023 - Elsevier
Compounds containing an Ssingle bondF bond have garnered intense interest in the
chemical and biological literature. In particular, sulfonyl fluorides (RSO 2 F) are commonly …

Indole-based derivatives as potential antibacterial activity against methicillin-resistance Staphylococcus aureus (MRSA)

HL Qin, J Liu, WY Fang, L Ravindar… - European journal of …, 2020 - Elsevier
Antibacterial-resistance speaks to an overall alarm, particularly in regards to the flare-up of
methicillin-resistance Staphylococcus aureus (MRSA), a classic reason for genuine skin and …

A key review on oxadiazole analogs as potential methicillin-resistant Staphylococcus aureus (MRSA) activity: Structure-activity relationship studies

SK Verma, R Verma, KSS Kumar, L Banjare… - European journal of …, 2021 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) is becoming dangerous to human
beings due to easy transmission mode and leading to the difficult-to-treat situation. The rapid …

[HTML][HTML] Emerging trends and future opportunities for coumarin-heterocycle conjugates as antibacterial agents

YF Mustafa - Results in Chemistry, 2023 - Elsevier
Infectious diseases resulting from various strains of pathogenic bacteria are among the
leading causes of death and morbidity worldwide. The currently-available antibacterial …

Antimicrobial peptides: An alternative to traditional antibiotics

S Ji, F An, T Zhang, M Lou, J Guo, K Liu, Y Zhu… - European Journal of …, 2023 - Elsevier
As antibiotic-resistant bacteria and genes continue to emerge, the identification of effective
alternatives to traditional antibiotics has become a pressing issue. Antimicrobial peptides …

Structure-activity relationships (SAR) of triazine derivatives: Promising antimicrobial agents

H Liu, S Long, KP Rakesh, GF Zha - European journal of medicinal …, 2020 - Elsevier
The emergence of drug resistance has created unmet medical need for the development of
new classes of antibiotics. Innovation of new antibacterial agents with new mode of action …

1, 2, 3-Triazole-containing hybrids with potential antibacterial activity against ESKAPE pathogens

C Deng, H Yan, J Wang, K Liu, B Liu, Y Shi - European Journal of …, 2022 - Elsevier
ESKAPE pathogens, as priority 1 and 2 pathogens, are prevalent infectious agents
associated with high morbidity and mortality. ESKAPE can cause broad-spectrum diseases …