Recent technological advances have expanded the breadth of available omic data, from
whole-genome sequencing data, to extensive transcriptomic, methylomic and metabolomic …

Evidence for a major role of genetic factors in the determination of body mass index (BMI)
comes from studies of related individuals. Despite consistent evidence for a heritable …

It was unknown whether plasma protein levels can be estimated based on DNA methylation
(DNAm) levels, and if so, how the resulting surrogates can be consolidated into a powerful …

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic
outcomes, independent of overall adiposity. To increase our understanding of the genetic …

To better determine the history of modern birds, we performed a genome-scale phylogenetic
analysis of 48 species representing all orders of Neoaves using phylogenomic methods …

Intestinal microbiota is known to be important in health and disease. Its composition is
influenced by both environmental and host factors. Few large-scale studies have evaluated …

Hemispheric asymmetry is a cardinal feature of human brain organization. Altered brain
asymmetry has also been linked to some cognitive and neuropsychiatric disorders. Here, the …

Importance Tourette syndrome (TS) is characterized by high rates of psychiatric comorbidity;
however, few studies have fully characterized these comorbidities. Furthermore, most …

Composed of hundreds of microbial species, the composition of the human gut microbiota
can vary with chronic diseases underlying health disparities that disproportionally affect …

Incomplete lineage sorting (ILS) makes ancestral genetic polymorphisms persist during
rapid speciation events, inducing incongruences between gene trees and species trees. ILS …